SCHEMBL13870922

SCHEMBL13870922

COc1cc2ccc(-c3cc(C)cc(C)c3)nc2cc1OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
KDM4E B2RXH2 3/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
PDGFRB P09619 8/20 0.46
PDGFRA P16234 8/20 0.46
HTT P42858 1/20 0.44
GLA P06280 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
NQO2 P16083 1/20 0.43
BRD4 O60885 1/20 0.41
PDE3B Q13370 1/20 0.40
PDE3A Q14432 1/20 0.40
SLC2A1 P11166 1/20 0.39
RAC1 P63000 1/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13870921 0.85 SMN1; SMN2 (0.54) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL16487810 0.85 KDM4E (0.40) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL28596277 0.81 SMN1; SMN2 (0.66) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL29501311 0.81 SMN1; SMN2 (0.66) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL13870794 0.80 NPC1 (0.40) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL13870820 0.80 KDM4E (0.49) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL13870939 0.80 KDM4E (0.55) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL14500753 0.80 NCF1 (0.54) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL13647152 0.80 CYP1A2 (0.42) ALDH1A1KDM4ERAB9APDGFRBPDGFRA
SCHEMBL13870932 0.80 MAOA (0.44) ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 US disclosed
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IK, G6PD, EYA2 ALDH1A1 111/4885SMN1; SMN2 4169/4885KDM4E 2874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.