Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.45 |
| ▸ | PPARG | P37231 | 7/20 | 0.45 |
| ▸ | MPC2 | O95563 | 2/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13876145 | 0.92 | CA2 (0.43) | ALDH1A1NPSR1PTPN1FFAR1PPARG | |
| SCHEMBL13875580 | 0.91 | PTPN1 (0.46) | ALDH1A1NPSR1PTPN1FFAR1PPARG | |
| SCHEMBL13875929 | 0.91 | PTPN1 (0.55) | ALDH1A1NPSR1PTPN1FFAR1PPARG | |
| SCHEMBL13866912 | 0.89 | ALDH1A1 (0.51) | ALDH1A1NPSR1PTPN1FFAR1PPARG | |
| SCHEMBL13908674 | 0.89 | ALDH1A1 (0.51) | ALDH1A1NPSR1PTPN1FFAR1PPARG | |
| SCHEMBL13875694 | 0.88 | PPARG (0.52) | ALDH1A1NPSR1FFAR1PPARGMPC2 | |
| SCHEMBL13912042 | 0.88 | PPARG (0.52) | ALDH1A1NPSR1FFAR1PPARGMPC2 | |
| Hydrochloric Acid SCHEMBL3868312 | 0.88 | ALDH1A1 (0.50) | ALDH1A1NPSR1PTPN1FFAR1PPARG | |
| SCHEMBL17365879 | 0.85 | CA2 (0.47) | ALDH1A1NPSR1FFAR1PPARGMPC2 | |
| SCHEMBL13876150 | 0.83 | CA2 (0.43) | ALDH1A1NPSR1PTPN1FFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848700-B1 | SALTS OF (S)-2-AMINO-3-{4-[4-(2,4-DIOXO-THIAZOLIDIN-5-YLMETHYL)-PHENOXY]-PHENYL}-PROPIONIC ACID AND ITS METHYL ESTER AS INTERLEUKIN INHIBITORS FOR THE TREATMENT OF OBESITY OR DIABETES | BEXEL PHARMACEUTICALS INC (US) | 2015-12-30 | — | — | EP | disclosed |
| US-7521465-B2 | Diphenyl ether derivatives | BEXEL PHARMACEUTICALS, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| US-20090069313-A1 | Novel MAO-A inhibitors | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069313-A1 | Novel MAO-A inhibitors | MAOA, MAOB, BACE1 | ALDH1A1 248/4885NPSR1 398/4885PTPN1 2404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.