Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 1/20 | 0.35 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | ADGRF1 | Q5T601 | 1/20 | 0.35 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14542190 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HSD17B10OPRK1GAAKMT2A | |
| SCHEMBL14542192 | 0.79 | GAA (0.48) | ALDH1A1HSD17B10GAAKMT2ACACNA1B | |
| SCHEMBL14542443 | 0.78 | ACE (0.48) | KMT2ACACNA1B | |
| SCHEMBL13879329 | 0.76 | DPP4 (0.40) | ALDH1A1GAAKMT2A | |
| SCHEMBL3936988 | 0.76 | LMNA (0.54) | ALDH1A1HSD17B10KMT2ASMN1; SMN2 | |
| SCHEMBL14031838 | 0.73 | ALDH1A1 (0.39) | ALDH1A1GAAKMT2AATMSMN1; SMN2 | |
| SCHEMBL27559390 | 0.73 | SLC7A5 (0.50) | ALDH1A1HSD17B10CHRM2KMT2ASMN1; SMN2 | |
| SCHEMBL5151943 | 0.71 | ACE (0.54) | ALDH1A1HSD17B10KMT2ACACNA1BATM | |
| SCHEMBL3936484 | 0.71 | ACE (0.54) | ALDH1A1HSD17B10KMT2ACACNA1BATM | |
| SCHEMBL3936455 | 0.71 | ACE (0.54) | ALDH1A1HSD17B10KMT2ACACNA1BATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945621-B1 | PROCESS TO PREPARE AMINO ACID DERIVATIVES | REDDY S LAB EU LTD DR (GB) | 2009-04-15 | — | — | EP | disclosed |