Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14542190 | 0.89 | ALDH1A1 (0.44) | GAAKMT2AALDH1A1HSD17B10ACE | |
| SCHEMBL3936988 | 0.88 | LMNA (0.54) | KMT2AALDH1A1HSD17B10ACELMNA | |
| SCHEMBL14542443 | 0.77 | ACE (0.48) | L3MBTL1KMT2AACECACNA1B | |
| SCHEMBL15498913 | 0.76 | ATM (0.50) | CYP2C9CYP2C19CYP3A4CYP2D6ATM | |
| SCHEMBL2856548 | 0.76 | NOS2 (0.58) | CYP2C9CYP2C19ATML3MBTL1KMT2A | |
| SCHEMBL29469535 | 0.76 | NOS2 (0.58) | CYP2C9CYP2C19ATML3MBTL1KMT2A | |
| SCHEMBL2856542 | 0.76 | NOS2 (0.58) | CYP2C9CYP2C19ATML3MBTL1KMT2A | |
| SCHEMBL13879329 | 0.76 | DPP4 (0.40) | GAADPP4KMT2AALDH1A1 | |
| SCHEMBL5151943 | 0.75 | ACE (0.54) | ATML3MBTL1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL3936455 | 0.75 | ACE (0.54) | ATML3MBTL1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038116-A1 | PROCESS TO PREPARE AMINO ACID DERIVATIVES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-04-05 | — | — | WO | disclosed |