Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.46 |
| ▸ | ACE | P12821 | 5/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.46 |
| ▸ | MME | P08473 | 4/20 | 0.46 |
| ▸ | CPA1 | P15085 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14542190 | 0.91 | ALDH1A1 (0.44) | LMNAALDH1A1HSD17B10ACEKMT2A | |
| SCHEMBL14542192 | 0.88 | GAA (0.48) | LMNAALDH1A1HSD17B10ACEKMT2A | |
| SCHEMBL3936484 | 0.84 | ACE (0.54) | ALDH1A1HSD17B10ITGB3ITGA2BITGA4 | |
| SCHEMBL3936490 | 0.84 | ACE (0.54) | ALDH1A1HSD17B10ITGB3ITGA2BITGA4 | |
| SCHEMBL3936455 | 0.84 | ACE (0.54) | ALDH1A1HSD17B10ITGB3ITGA2BITGA4 | |
| SCHEMBL5151943 | 0.84 | ACE (0.54) | ALDH1A1HSD17B10ITGB3ITGA2BITGA4 | |
| SCHEMBL27559390 | 0.82 | SLC7A5 (0.50) | LMNAALDH1A1HSD17B10KMT2AKDM4E | |
| SCHEMBL13879329 | 0.78 | DPP4 (0.40) | ALDH1A1KMT2A | |
| SCHEMBL13879233 | 0.76 | ALDH1A1 (0.37) | ALDH1A1HSD17B10KMT2ASMN1; SMN2 | |
| SCHEMBL5994613 | 0.75 | LMNA (0.63) | LMNAALDH1A1ITGB3ITGA2BACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945621-B1 | PROCESS TO PREPARE AMINO ACID DERIVATIVES | REDDY S LAB EU LTD DR (GB) | 2009-04-15 | — | — | EP | disclosed |