Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13891714 | 0.88 | ADORA2A (0.40) | ADORA2AMAOBGAAKDM4ERECQL | |
| SCHEMBL13891686 | 0.86 | MAPT (0.35) | MAPTMEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL13891740 | 0.71 | TLR7 (0.36) | MEN1KMT2ATSHRCYP3A4CYP2C19 | |
| SCHEMBL13891713 | 0.68 | TACR1 (0.42) | TACR1 | |
| SCHEMBL13891767 | 0.68 | P2RX3 (0.40) | ACHEMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL13891721 | 0.67 | HTT (0.37) | GAAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL13891766 | 0.65 | KDM4E (0.38) | KDM4ETACR1HSD17B10MAPTMEN1 | |
| SCHEMBL5236630 | 0.65 | TACR1 (0.37) | KDM4ETACR1MAPTALDH1A1 | |
| SCHEMBL13891688 | 0.64 | TACR1 (0.41) | TACR1KMT2ATSHR | |
| SCHEMBL5230109 | 0.63 | TACR1 (0.39) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1473295-B1 | FUSED BICYCLIC PYRIMIDINE DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2009-04-01 | — | — | EP | disclosed |