Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10336410 | 0.80 | HSD17B10 (0.48) | TSHRHSD17B10ALDH1A1CYP3A4TDP1 | |
| SCHEMBL16359042 | 0.78 | CA12 (0.58) | MAPTKDM4ECA12CA1CA2 | |
| SCHEMBL1121596 | 0.77 | TSHR (0.68) | TSHRHSD17B10ALDH1A1CYP3A4TDP1 | |
| SCHEMBL8261015 | 0.76 | MAOA (0.46) | TSHRCYP3A4SRD5A2 | |
| SCHEMBL13008247 | 0.73 | ALOX15 (0.50) | TSHRHSD17B10ALDH1A1CYP3A4HPGD | |
| SCHEMBL3566736 | 0.73 | TSHR (0.50) | TSHRHSD17B10ALDH1A1CYP3A4TDP1 | |
| SCHEMBL20444303 | 0.71 | ALDH1A1 (0.50) | TSHRHSD17B10ALDH1A1CYP3A4TDP1 | |
| SCHEMBL8020903 | 0.71 | PKM (0.50) | TSHRHSD17B10ALDH1A1CYP3A4TDP1 | |
| SCHEMBL27242081 | 0.71 | LMNA (0.50) | TSHRHSD17B10ALDH1A1CYP3A4TDP1 | |
| SCHEMBL1936725 | 0.71 | LCK (0.53) | TSHRHSD17B10ALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048140-A1 | Deuterated chemiluminescent 1,2-dioxetanes | Giri, Brij P. (US) | 2009-04-15 | — | — | EP | disclosed |