Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13839404 | 0.83 | ACE (0.43) | CTSLFKBP1AACE | |
| SCHEMBL27643156 | 0.82 | ACE (0.53) | CTSLACE | |
| SCHEMBL13895644 | 0.82 | ACE (0.53) | CTSLACE | |
| SCHEMBL3882949 | 0.82 | KMT2A (0.40) | CTSLPREPITGB3ITGA2BCMA1 | |
| SCHEMBL9699149 | 0.79 | PREP (0.61) | CTSLPREPFKBP1ACMA1KLK5 | |
| SCHEMBL10882017 | 0.79 | PREP (0.61) | CTSLPREPFKBP1ACMA1KLK5 | |
| SCHEMBL7265704 | 0.79 | PREP (0.61) | CTSLPREPFKBP1ACMA1KLK5 | |
| SCHEMBL28545846 | 0.79 | PREP (0.61) | CTSLPREPFKBP1ACMA1KLK5 | |
| SCHEMBL10842684 | 0.76 | ACE (0.53) | CTSLPREPACE | |
| SCHEMBL9256682 | 0.76 | CTSL (0.54) | CTSLPREPFKBP1AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157485-B2 | Method for synthesizing derivatives of (2S,3AS,7AS)-1-[(S)-alanyl]-octahydro,-1H-indole-2-carboxylic acid and the use thereof for perindopril synthesis | LES LABORATOIRES SERVIER (FR) | 2007-01-02 | — | — | US | disclosed |
| US-20060149082-A1 | Novel method for synthesising derivatives of (2s,3as,7as)-1-[(s)-alanyl]-octahydro,-1h-indole-2-carboxylic acid and the use thereof for perindopril synthesis | LES LABORATOIRES SERVIER (FR) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060149082-A1 | Novel method for synthesising derivatives of (2s,3as,7as)-1-[(s)-alanyl]-octahydro,-1h-indole-2-carboxylic acid and the use thereof for perindopril synthesis | AGTR1, CYP2S1, PAH | CTSL 743/4885PREP 342/4885ITGB3 3990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.