Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | MGAT2 | Q10469 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975525 | 0.82 | MMP2 (0.48) | ALDH1A1ADAM17KCNH2MMP2MMP9 | |
| SCHEMBL14350057 | 0.78 | MMP2 (0.35) | MAPK1ALDH1A1ADAM17MGAT2SLC6A2 | |
| SCHEMBL542561 | 0.68 | LMNA (0.53) | MAPK1ALDH1A1ADAM17KCNH2HSD17B10 | |
| SCHEMBL20134878 | 0.68 | LMNA (0.53) | MAPK1ALDH1A1ADAM17KCNH2HSD17B10 | |
| SCHEMBL9717712 | 0.67 | POLB (0.32) | KDM4ELMNAPOLB | |
| SCHEMBL13527600 | 0.67 | POLB (0.32) | KDM4ELMNAPOLB | |
| SCHEMBL3968265 | 0.66 | CNR1 (0.39) | ALDH1A1KCNH2MMP2MMP9CYP2C9 | |
| SCHEMBL10521481 | 0.65 | CYP2C9 (0.64) | ALDH1A1ADAM17SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL5447642 | 0.64 | MMP2 (0.44) | ALDH1A1ADAM17SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL19732182 | 0.61 | ACHE (0.44) | ALDH1A1SLC6A2SLC6A3SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7501523-B2 | reacting an oligomer consisting of 2-11 linked glycolurils or analogues with one or more compounds selected from glycoluril, glycoluril analogues and/or oligomers of glycoluril or glycoluril analogues, in the presence of an acid, and a template (dimethylaminobenzaldehyde) to form a cucurbit(n)uril | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2009-03-10 | — | — | US | disclosed |
| US-20070287836-A1 | Method for Preparing Compounds Comprising Cucurbituril Groups | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2007-12-13 | — | — | US | disclosed |
| US-20070066818-A1 | Method for preparing cucurbiturils | ANTHONY IVAN DAY (AU) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287836-A1 | Method for Preparing Compounds Comprising Cucurbituril Groups | ACSL6, AGL, LIPA | MAPK1 3587/4885ALDH1A1 93/4885ADAM17 4391/4885 |
| US-20070066818-A1 | Method for preparing cucurbiturils | AGL, UGCG, MGLL | MAPK1 3168/4885ALDH1A1 1186/4885ADAM17 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.