Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.44 |
| ▸ | MMP9 | P14780 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477539 | 0.78 | MMP2 (0.41) | MMP2MMP9HTTMMP8ADAM17 | |
| SCHEMBL9841218 | 0.77 | NPSR1 (0.43) | MMP2MMP9ADAM17MMP13MMP14 | |
| SCHEMBL2615290 | 0.75 | MMP2 (0.67) | MMP2MMP9HTTMMP8ADAM17 | |
| SCHEMBL3207324 | 0.74 | MMP9 (0.59) | MMP2MMP9MMP8MMP3MMP13 | |
| SCHEMBL3195931 | 0.74 | MMP9 (0.59) | MMP2MMP9MMP8MMP3MMP13 | |
| SCHEMBL1861823 | 0.74 | MMP9 (0.59) | MMP2MMP9MMP8MMP3MMP13 | |
| SCHEMBL10521481 | 0.74 | CYP2C9 (0.64) | MMP2MMP9HTTMMP8ADAM17 | |
| SCHEMBL542561 | 0.72 | LMNA (0.53) | MMP2MMP9ADAM17KCNH2LMNA | |
| SCHEMBL20134878 | 0.72 | LMNA (0.53) | MMP2MMP9ADAM17KCNH2LMNA | |
| SCHEMBL20134752 | 0.69 | ADAM17 (0.45) | MMP2MMP9HTTMMP8ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | L'OREAL S.A. | 2007-06-14 | — | — | US | claimed |
| US-20050262647-A1 | Agent for dyeing fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2005-12-01 | — | — | US | disclosed |
| EP-0137343-B1 | NOVEL OXOPYRIMIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Taro Pharmaceutical Industries Ltd. (IL) | 1991-12-04 | — | — | EP | disclosed |
| US-4628056-A | Novel oxopyrimidine derivatives, pharmaceutical compositions containing them and their use as anticonvulsant, antianxiety and muscle relaxant agents | TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1986-12-09 | — | — | US | disclosed |
| EP-0137343-A2 | Novel oxopyrimidine derivatives and pharmaceutical compositions containing them | Taro Pharmaceutical Industries Ltd. (IL) | 1985-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | KRT18, NDUFB5, NDUFB7 | MMP2 1459/4885MMP9 3661/4885HTT 3885/4885 |
| US-20050262647-A1 | Agent for dyeing fibers containing keratin | KRT18, CKAP4, KRTCAP2 | MMP2 1928/4885MMP9 4222/4885HTT 1656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.