Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.57 |
| ▸ | CA9 | Q16790 | 6/20 | 0.57 |
| ▸ | CA1 | P00915 | 4/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.57 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9967354 | 0.88 | MAPT (0.50) | CA12CA9CA1CA2SCN2A | |
| SCHEMBL15081256 | 0.88 | CA12 (0.43) | CA12CA9CA1CA2SCN2A | |
| SCHEMBL303331 | 0.85 | ALDH1A1 (0.51) | NPSR1ALDH1A1MAPTPKMHTT | |
| SCHEMBL28170453 | 0.84 | NPSR1 (0.47) | NPSR1SMN1; SMN2ALDH1A1MAPTPKM | |
| SCHEMBL1471161 | 0.82 | MAPT (0.50) | NPSR1ALDH1A1MAPTHTTPTGES | |
| SCHEMBL1471657 | 0.81 | MAPT (0.54) | NPSR1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL1471189 | 0.81 | ALDH1A1 (0.57) | NPSR1KDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1473687 | 0.81 | MGLL (0.47) | NPSR1KDM4EALDH1A1MAPTHTT | |
| SCHEMBL1471136 | 0.81 | MGLL (0.47) | CA12CA9CA1CA2SCN2A | |
| SCHEMBL28976650 | 0.81 | ALDH1A1 (0.45) | NPSR1ALDH1A1MAPTHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507784-B2 | Liquid crystalline thermosets from ester, ester-imide, and ester-amide oligomers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2009-03-24 | — | — | US | disclosed |
| US-7507784-B2 | Liquid crystalline thermosets from ester, ester-imide, and ester-amide oligomers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2009-03-24 | — | — | US | disclosed |