SCHEMBL9967354

SCHEMBL9967354

CC(=O)c1ccc(N2C(=O)C=C(c3ccccc3)C2=O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ ALDH1A1 P00352 4/20 0.47
▸ CA9 Q16790 2/20 0.43
▸ CA12 O43570 1/20 0.43
▸ CA1 P00915 1/20 0.43
▸ CA2 P00918 1/20 0.43
▸ SCN2A Q99250 1/20 0.43
▸ NPC1 O15118 1/20 0.42
▸ RAB9A P51151 1/20 0.42
▸ KMT2A Q03164 3/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ HPGD P15428 3/20 0.41
▸ GAA P10253 2/20 0.41
▸ CCR6 P51684 2/20 0.41
▸ NPSR1 Q6W5P4 2/20 0.41
▸ ALOX12 P18054 1/20 0.41
▸ CACNA1B Q00975 1/20 0.41
▸ APBA1 Q02410 1/20 0.41
▸ ADAM17 P78536 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13900311 0.88 CA12 (0.57) MAPTSMN1; SMN2ALDH1A1CA9CA12
SCHEMBL10884164 0.86 KMT2A (0.40) MAPTSMN1; SMN2ALDH1A1CA9CA12
SCHEMBL15081256 0.85 CA12 (0.43) MAPTALDH1A1CA9CA12CA1
SCHEMBL303331 0.82 ALDH1A1 (0.51) MAPTALDH1A1KMT2AMEN1HPGD
SCHEMBL13900316 0.82 GLA (0.51) MAPTSMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL1471189 0.81 ALDH1A1 (0.57) MAPTSMN1; SMN2ALDH1A1KMT2AMEN1
SCHEMBL28170453 0.81 NPSR1 (0.47) MAPTSMN1; SMN2ALDH1A1KMT2AHPGD
SCHEMBL1471161 0.80 MAPT (0.50) MAPTALDH1A1NPC1RAB9AKMT2A
SCHEMBL1473687 0.78 MGLL (0.47) MAPTALDH1A1NPC1KMT2AMEN1
SCHEMBL1471657 0.78 MAPT (0.54) MAPTALDH1A1NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9023559-B2 Positive photosensitive resin composition, photosensitive resin film prepared by using the same, and semiconductor device including the photosensitive resin film CHEIL INDUSTRIES INC. (KR) 2015-05-05 — — US disclosed
US-8841064-B2 Positive photosensitive resin composition, photosensitive resin film prepared by using the same, and semiconductor device including the photosensitive resin film CHEIL INDUSTRIES INC. (KR) 2014-09-23 — — US disclosed
US-8815489-B2 Positive photosensitive resin composition, photosensitive resin film prepared by using the same, and semiconductor device including the photosensitive resin film CHEIL INDUSTRIES INC. (KR) 2014-08-26 — — US disclosed
US-8785103-B2 Photosensitive novolac resin, positive photosensitive resin composition including same, photosensitive resin film prepared by using the same, and semiconductor device including the photosensitive resin film CHEIL INDUSTRIES INC. (KR) 2014-07-22 — — US disclosed
US-20130171563-A1 Photosensitive Novolac Resin, Positive Photosensitive Resin Composition Including Same, Photosensitive Resin Film Prepared by Using the Same, and Semiconductor Device Including the Photosensitive Resin Film CHEIL INDUSTRIES INC. (KR) 2013-07-04 — — US disclosed
US-20130137036-A1 Positive Photosensitive Resin Composition, Photosensitive Resin Film Prepared by Using the Same, and Semiconductor Device Including the Photosensitive Resin Film CHEIL INDUSTRIES INC. (KR) 2013-05-30 — — US disclosed
US-8420287-B2 Positive photosensitive resin composition CHEIL INDUSTRIES INC. (KR) 2013-04-16 — — US disclosed
US-20120171610-A1 Positive Photosensitive Resin Composition, Photosensitive Resin Film Prepared by Using the Same, and Semiconductor Device Including the Photosensitive Resin Film CHEIL INDUSTRIES INC. (KR) 2012-07-05 — — US disclosed
US-20120171614-A1 Positive Photosensitive Resin Composition, Photosensitive Resin Film Prepared by Using the Same, and Semiconductor Device Including the Photosensitive Resin Film CHEIL INDUSTRIES INC. (KR) 2012-07-05 — — US disclosed
US-20120171609-A1 Positive Photosensitive Resin Composition, Photosensitive Resin Layer Prepared by Using the Same, and Semiconductor Device Including the Photosensitive Resin Layer CHEIL INDUSTRIES INC. (KR) 2012-07-05 — — US disclosed
US-20120156614-A1 Novel Phenol Compounds and Positive Photosensitive Resin Composition Including the Same SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-06-21 — — US disclosed
US-20110111346-A1 Positive Photosensitive Resin Composition CHEIL INDUSTRIES INC. (KR) 2011-05-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120156614-A1 Novel Phenol Compounds and Positive Photosensitive Resin Composition Including the Same SUN2, TYR, PSMD2 MAPT 1621/4885SMN1; SMN2 4759/4885ALDH1A1 1848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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