Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13898949 | 0.79 | MMP1 (0.48) | NR3C1LMNAPTGESALOX5MMP1 | |
| SCHEMBL6813465 | 0.77 | MMP1 (0.55) | NR3C1LMNAMMP1MAPTALDH1A1 | |
| SCHEMBL6813135 | 0.77 | MMP1 (0.67) | NR3C1PTGESMMP1MAPTKEAP1 | |
| SCHEMBL6809611 | 0.76 | MMP1 (0.54) | NR3C1PTGESMMP1KEAP1NFE2L2 | |
| SCHEMBL13902863 | 0.75 | MMP1 (0.45) | NR3C1LMNAPTGESALOX5MMP1 | |
| SCHEMBL13898698 | 0.74 | MMP1 (0.49) | LMNAMMP1CA1CA2MMP13 | |
| SCHEMBL13898761 | 0.73 | NR3C1 (0.37) | NR3C1LMNAPTGESALOX5MMP1 | |
| SCHEMBL6872277 | 0.72 | MMP1 (0.43) | NR3C1LMNAPTGESMMP1MAPT | |
| SCHEMBL6872275 | 0.72 | MMP1 (0.43) | NR3C1LMNAPTGESMMP1MAPT | |
| SCHEMBL6813134 | 0.72 | MMP1 (0.47) | NR3C1PTGESMMP1KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |