Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400264 | 0.79 | FFAR1 (0.50) | FFAR1KDM4ELMNA | |
| SCHEMBL5352838 | 0.79 | LOXL2 (0.53) | FFAR1MMP2 | |
| SCHEMBL8760838 | 0.77 | BCHE (0.73) | FFAR1BCHEGID4SPHK2SPHK1 | |
| SCHEMBL1807496 | 0.76 | MEN1 (0.61) | FFAR1ALDH1A1KDM4E | |
| SCHEMBL26968221 | 0.73 | CHEK1 (0.46) | FFAR1 | |
| SCHEMBL7399916 | 0.72 | ALDH1A1 (0.52) | FFAR1ALDH1A1KDM4ELMNA | |
| SCHEMBL30172106 | 0.72 | PKM (0.56) | ALDH1A1 | |
| SCHEMBL4984973 | 0.71 | CA2 (0.48) | FFAR1KDM4ELMNA | |
| SCHEMBL9515149 | 0.71 | POLB (0.53) | FFAR1ALDH1A1KDM4E | |
| SCHEMBL287925 | 0.71 | CA2 (0.54) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507757-B2 | Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-03-24 | — | — | US | disclosed |