SCHEMBL13930707

SCHEMBL13930707

COc1ccc(NC(=O)CC2CCN([C@H](C)CN(c3cccc(C(=N)N)c3)S(=O)(=O)Cc3ccccc3)CC2)cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ UBE2M P61081 4/20 0.44
▸ DCUN1D1 Q96GG9 4/20 0.44
▸ F10 P00742 6/20 0.43
▸ F2 P00734 5/20 0.43
▸ PRSS1 P07477 1/20 0.43
▸ PRSS2 P07478 1/20 0.43
▸ PRSS3 P35030 1/20 0.43
▸ PLG P00747 2/20 0.42
▸ PLAU P00749 2/20 0.42
▸ ST14 Q9Y5Y6 2/20 0.42
▸ TPSAB1 Q15661 1/20 0.41
▸ EPHX2 P34913 1/20 0.41
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ OPRM1 P35372 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13930717 0.93 UBE2M (0.45) UBE2MDCUN1D1EPHX2MEN1KMT2A
SCHEMBL13930715 0.92 UBE2M (0.46) UBE2MDCUN1D1EPHX2MEN1KMT2A
SCHEMBL13930704 0.92 TPSAB1 (0.46) UBE2MDCUN1D1PLAUTPSAB1EPHX2
SCHEMBL13930692 0.90 UBE2M (0.49) UBE2MDCUN1D1EPHX2MEN1KMT2A
SCHEMBL13930718 0.88 TPSAB1 (0.51) UBE2MDCUN1D1TPSAB1OPRM1
SCHEMBL13930716 0.86 UBE2M (0.46) UBE2MDCUN1D1EPHX2MEN1KMT2A
SCHEMBL13930712 0.85 SMN1; SMN2 (0.49) UBE2MDCUN1D1EPHX2MEN1KMT2A
SCHEMBL13930730 0.84 UBE2M (0.51) UBE2MDCUN1D1OPRM1
SCHEMBL13952184 0.82 OPRM1 (0.45) UBE2MDCUN1D1EPHX2OPRM1
SCHEMBL13930670 0.80 OPRM1 (0.47) OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090048291-A1 Novel Piperidine-4-Acetic Acid Derivatives and Their Use EUROSCREEN S.A. (BE) 2009-02-19 — — US disclosed
US-20090048291-A1 Novel Piperidine-4-Acetic Acid Derivatives and Their Use EUROSCREEN S.A. (BE) 2009-02-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090048291-A1 Novel Piperidine-4-Acetic Acid Derivatives and Their Use ALDH1A1, ABAT, ALDH18A1 UBE2M 3695/4885DCUN1D1 3824/4885F10 4733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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