Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.55 |
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13934698 | 0.92 | CTSK (0.53) | CTSKCTSSPSENENCA2 | |
| SCHEMBL13934352 | 0.92 | CTSK (0.53) | CTSKCTSSPSENENCA2 | |
| SCHEMBL13921041 | 0.88 | CTSS (0.55) | CTSKCTSSPSENENCA2CTSD | |
| SCHEMBL22068618 | 0.83 | CTSS (0.65) | CTSKCTSSPSENENCA2CTSD | |
| SCHEMBL22068619 | 0.83 | CTSS (0.65) | CTSKCTSSPSENENCA2CTSD | |
| SCHEMBL31139338 | 0.82 | CTSS (0.64) | CTSKCTSSPSENENCA2CTSD | |
| SCHEMBL9754306 | 0.82 | PSENEN (0.71) | CTSKCTSSPSENENCA2CTSD | |
| SCHEMBL31139352 | 0.82 | CTSS (0.64) | CTSKCTSSPSENENCA2CTSD | |
| SCHEMBL8492292 | 0.80 | CTSS (0.61) | CTSKCTSSPSENENCA2CTSD | |
| SCHEMBL8492297 | 0.80 | CTSS (0.61) | CTSKCTSSPSENENCA2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498353-B2 | Heterocyclic anti-viral compounds comprising metabolizable moieties and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2009-03-03 | — | — | US | disclosed |