Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979688 | 0.96 | STS (0.60) | STSMAPK1GPR119KMT2APTPN2 | |
| SCHEMBL13938196 | 0.88 | FKBP1A (0.49) | STSMAPK1HPGDGPR119 | |
| SCHEMBL13938199 | 0.87 | KDM4E (0.50) | STSMAPK1HPGDGPR119KMT2A | |
| SCHEMBL3917709 | 0.87 | GPR119 (0.51) | STSMAPK1GPR119KMT2AALDH1A1 | |
| SCHEMBL1980404 | 0.86 | HSD17B10 (0.53) | STSMAPK1KMT2ASFRP1 | |
| SCHEMBL1979225 | 0.86 | USP30 (0.50) | STSMAPK1HPGDGPR119KMT2A | |
| SCHEMBL13938181 | 0.84 | ALDH1A1 (0.48) | KMT2AALDH1A1USP2KDM4EBLM | |
| SCHEMBL3266038 | 0.83 | YAP1 (0.60) | STSGPR119KDM4EPKM | |
| SCHEMBL3921527 | 0.83 | MAPK1 (0.49) | STSMAPK1GPR119KMT2A | |
| SCHEMBL3266040 | 0.83 | STS (0.45) | STSMAPK1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7476680-B2 | Substituted heterocyclic compounds for treating multidrug resistance | H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE, INC. (US) | 2009-01-13 | — | — | US | disclosed |
| US-7476680-B2 | Substituted heterocyclic compounds for treating multidrug resistance | H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE, INC. (US) | 2009-01-13 | — | — | US | disclosed |