Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.50 |
| ▸ | WNT3 | P56703 | 2/20 | 0.48 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1986802 | 0.93 | FKBP1A (0.48) | HSD17B10MEN1KMT2AFKBP1AWNT3 | |
| SCHEMBL1979768 | 0.90 | FKBP1A (0.52) | MEN1KMT2AFKBP1APIN1F2 | |
| SCHEMBL1979169 | 0.90 | FKBP1A (0.55) | MEN1KMT2AFKBP1APIN1F2 | |
| SCHEMBL13938196 | 0.89 | FKBP1A (0.49) | FKBP1ASTSMAPK1PIN1F2 | |
| SCHEMBL13938176 | 0.86 | STS (0.56) | KMT2ASFRP1STSMAPK1 | |
| SCHEMBL1979688 | 0.86 | STS (0.60) | KMT2ASTSMAPK1 | |
| SCHEMBL13938201 | 0.84 | FKBP1A (0.48) | KMT2AFKBP1APIN1F2PRSS1 | |
| SCHEMBL3266040 | 0.81 | STS (0.45) | MEN1KMT2AFKBP1ASTSMAPK1 | |
| SCHEMBL1979225 | 0.81 | USP30 (0.50) | MEN1KMT2ASTSMAPK1 | |
| SCHEMBL13938199 | 0.80 | KDM4E (0.50) | MEN1KMT2ASTSMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326834-B1 | 2-SUBSTITUTED HETEROCYCLIC COMPOUNDS | H LEE MOFFITT CANCER CT & RES (US) | 2011-06-29 | — | — | EP | disclosed |