Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 13/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239764 | 0.81 | HSD11B1 (0.57) | HSD11B1ALDH1A1POLBMAPK1GFER | |
| SCHEMBL3994121 | 0.80 | HSD11B1 (0.53) | HSD11B1ALDH1A1MALT1UTS2R | |
| SCHEMBL7172429 | 0.72 | LMNA (0.48) | ALDH1A1MALT1LMNAL3MBTL1POLB | |
| SCHEMBL7172425 | 0.72 | LMNA (0.48) | ALDH1A1MALT1LMNAL3MBTL1POLB | |
| SCHEMBL31601117 | 0.71 | TAAR1 (0.41) | HSD11B1ALDH1A1TAAR1L3MBTL1 | |
| SCHEMBL14142801 | 0.70 | TAAR1 (0.47) | HSD11B1ALDH1A1TAAR1LMNAL3MBTL1 | |
| SCHEMBL3209284 | 0.70 | TAAR1 (0.47) | HSD11B1ALDH1A1TAAR1LMNAL3MBTL1 | |
| SCHEMBL27805306 | 0.70 | TAAR1 (0.47) | HSD11B1ALDH1A1TAAR1LMNAL3MBTL1 | |
| SCHEMBL6288740 | 0.69 | ALDH1A1 (0.38) | ALDH1A1MALT1POLBMAPK1GFER | |
| SCHEMBL8114661 | 0.66 | HSD11B1 (0.36) | HSD11B1ALDH1A1TAAR1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473790-B2 | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same | PFIZER INC. (US) | 2009-01-06 | — | — | US | disclosed |
| US-7473790-B2 | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same | PFIZER INC. (US) | 2009-01-06 | — | — | US | disclosed |