Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 13/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13938809 | 0.81 | HSD11B1 (0.48) | HSD11B1ALDH1A1POLBMAPK1GFER | |
| SCHEMBL3994121 | 0.80 | HSD11B1 (0.53) | HSD11B1ALDH1A1HCAR3HCAR2 | |
| SCHEMBL9721330 | 0.76 | MEN1 (0.45) | HSD11B1ALDH1A1MEN1CYP2C9KMT2A | |
| SCHEMBL11220183 | 0.74 | HSD11B1 (0.46) | HSD11B1ALDH1A1 | |
| SCHEMBL27949831 | 0.73 | MEN1 (0.42) | HSD11B1ALDH1A1MEN1CYP2C9KMT2A | |
| SCHEMBL5940409 | 0.73 | MALT1 (0.69) | HSD11B1ALDH1A1MEN1CYP2C9KMT2A | |
| SCHEMBL955441 | 0.73 | HSD11B1 (0.49) | HSD11B1MEN1KMT2APOLBGRIN1 | |
| SCHEMBL9182623 | 0.73 | HCAR3 (0.42) | HSD11B1ALDH1A1MEN1CYP2C9KMT2A | |
| SCHEMBL957207 | 0.73 | HSD11B1 (1.00) | HSD11B1MEN1KMT2A | |
| SCHEMBL7172429 | 0.72 | LMNA (0.48) | ALDH1A1MEN1KMT2APOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4533720-A | WITH AN ANHYDRIDE IN REACTION MIXTURE | PHILLIPS PETROLEUM COMPANY (US) | 1985-08-06 | — | — | US | claimed |
| US-4308364-A | FOR ALKALI METAL-TERMINATED POLYMERS OF CONJUGATED DIENES AND/OR MONOVINYLARENES | PHILLIPS PETROLEUM COMPANY (US) | 1981-12-29 | — | — | US | claimed |
| CN-106831389-B | Method for producing carboxylic acid compound | 中国科学技术大学 | 2020-03-31 | — | — | CN | disclosed |
| EP-1201652-B1 | Process for the preparation of lactams | DAIREN CHEMICAL CORP (TW) | 2005-06-29 | — | — | EP | disclosed |
| CN-1120151-C | Process for preparing lactams | DALIAN CHEMICAL INDUSTRY CO LT (CN) | 2003-09-03 | — | — | CN | disclosed |
| US-20020120154-A1 | Method for preparing lactam | DAIREN CHEMICAL CORPORATION (TW) | 2002-08-29 | — | — | US | disclosed |
| CN-1349982-A | Process for preparing lactams | DALIAN CHEMICAL INDUSTRY CO LT (CN) | 2002-05-22 | — | — | CN | disclosed |
| EP-1201652-A1 | Process for the preparation of lactams | Dairen Chemical Corporation (TW) | 2002-05-02 | — | — | EP | disclosed |
| US-6350883-B1 | REACTION OF LACTONE WITH AMINE OR AMMONIA TO FORM A LACTAM | DAIREN CHEMICAL CORPORATION (TW) | 2002-02-26 | — | — | US | disclosed |
| US-4533720-A | WITH AN ANHYDRIDE IN REACTION MIXTURE | PHILLIPS PETROLEUM COMPANY (US) | 1985-08-06 | — | — | US | disclosed |
| US-4308364-A | FOR ALKALI METAL-TERMINATED POLYMERS OF CONJUGATED DIENES AND/OR MONOVINYLARENES | PHILLIPS PETROLEUM COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120154-A1 | Method for preparing lactam | AGL, APH1A, DCXR | HSD11B1 612/4885ALDH1A1 2367/4885MEN1 1372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.