Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CCR9 | P51686 | 2/20 | 0.58 |
| ▸ | METAP2 | P50579 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12220857 | 0.90 | LMNA (0.81) | LMNAHTTTP53MAPTKMT2A | |
| SCHEMBL14311492 | 0.87 | CCR9 (0.61) | LMNAHTTTP53MAPTKMT2A | |
| SCHEMBL11182634 | 0.85 | LMNA (1.00) | LMNAHTTTP53MAPTKMT2A | |
| SCHEMBL29148 | 0.85 | METAP2 (0.75) | LMNAHTTTP53MAPTKMT2A | |
| SCHEMBL27995 | 0.84 | ALDH1A1 (0.74) | LMNAHTTMAPTKMT2AALDH1A1 | |
| SCHEMBL13484207 | 0.84 | LMNA (0.72) | LMNAHTTTP53MAPTKMT2A | |
| SCHEMBL13137558 | 0.84 | LMNA (0.80) | LMNAHTTTP53MAPTKMT2A | |
| SCHEMBL2534878 | 0.83 | LMNA (0.86) | LMNAHTTTP53MAPTKMT2A | |
| SCHEMBL13483878 | 0.82 | LMNA (0.70) | LMNAHTTTP53MAPTKMT2A | |
| SCHEMBL16479405 | 0.81 | LMNA (0.71) | LMNAHTTTP53MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054495-A1 | CCR9 inhibitors and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054495-A1 | CCR9 inhibitors and methods of use thereof | CCR9, CCR1, CCR4 | LMNA 3548/4885HTT 4358/4885TP53 3735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.