Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13688358 | 0.95 | CYP3A4 (0.35) | ALDH1A1CYP1A2CYP3A4ABCB11LMNA | |
| SCHEMBL14019677 | 0.89 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL4002175 | 0.82 | CYP3A4 (0.32) | CYP1A2CYP3A4ABCB11LMNACHRM2 | |
| SCHEMBL13688355 | 0.82 | CYP3A4 (0.37) | ALDH1A1CYP1A2CYP3A4ABCB11LMNA | |
| SCHEMBL13688396 | 0.81 | — | — | |
| SCHEMBL14019694 | 0.81 | CYP3A4 (0.35) | CYP1A2CYP3A4ABCB11LMNACHRM2 | |
| SCHEMBL14019710 | 0.79 | CYP3A4 (0.32) | CYP1A2CYP3A4ABCB11LMNACHRM2 | |
| SCHEMBL13688383 | 0.79 | THRB (0.41) | ALDH1A1CYP1A2CYP3A4ABCB11LMNA | |
| SCHEMBL13688359 | 0.78 | EPHX2 (0.33) | CYP1A2CYP3A4ABCB11LMNACHRM2 | |
| SCHEMBL3998071 | 0.78 | CYP1A2 (0.34) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11135136-B2 | Dental materials based on urethane-group-containing vinylcyclopropane derivatives | IVOCLAR VIVADENT AG (LI) | 2021-10-05 | — | — | US | claimed |
| US-10660825-B2 | — | — | 2020-05-26 | — | — | US | claimed |
| US-20190167533-A1 | DENTAL MATERIALS BASED ON URETHANE-GROUP-CONTAINING VINYLCYCLOPROPANE DERIVATIVES | IVOCLAR VIVADENT AG (LI) | 2019-06-06 | — | — | US | claimed |
| EP-3278786-B1 | DENTAL MATERIALS ON THE BASIS OF VINYLCYCLOPROPANE DERIVATIVES CONTAINING URETHANE GROUPS | IVOCLAR VIVADENT AG (LI) | 2019-01-23 | — | — | EP | claimed |
| US-20180036209-A1 | Dental Materials Based on Monofunctional Vinylcyclopropane Derivatives | IVOCLAR VIVADENT AG (LI) | 2018-02-08 | — | — | US | claimed |
| US-20230322820-A1 | BISACYL DIGERMANIUM COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PHOTOINITIATOR FOR RADICAL POLYMERIZATION | EVONIK OPERATIONS GMBH (DE) | 2023-10-12 | — | — | US | disclosed |
| EP-4257592-A1 | BISACYL DIGERMANIUM COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PHOTOINITIATOR FOR RADICAL POLYMERIZATION | Evonik Operations GmbH (DE) | 2023-10-11 | — | — | EP | disclosed |
| US-11142592-B2 | Polymerizable compositions with acyltin photoinitiators | IVOCLAR VIVADENT AG (LI) | 2021-10-12 | — | — | US | disclosed |
| US-11135136-B2 | Dental materials based on urethane-group-containing vinylcyclopropane derivatives | IVOCLAR VIVADENT AG (LI) | 2021-10-05 | — | — | US | disclosed |
| US-10787468-B2 | Acyl germanium photoinitiators and process for the preparation thereof | IVOCLAR VIVADENT AG (LI) | 2020-09-29 | — | — | US | disclosed |
| US-10660825-B2 | — | — | 2020-05-26 | — | — | US | disclosed |
| US-20200087329-A1 | Acyl Germanium Photoinitiators And Process For The Preparation Thereof | IVOCLAR VIVADENT AG (LI) | 2020-03-19 | — | — | US | disclosed |
| US-20070232719-A1 | POLYMERIZABLE BICYCLIC CYCLOPROPANE DERIVATIVES AND THEIR USE FOR THE PREPARATION OF DENTAL MATERIALS | IVOCLAR VIVADENT AG (LI) | 2007-10-04 | — | — | US | disclosed |
| US-20070232719-A1 | POLYMERIZABLE BICYCLIC CYCLOPROPANE DERIVATIVES AND THEIR USE FOR THE PREPARATION OF DENTAL MATERIALS | IVOCLAR VIVADENT AG (LI) | 2007-10-04 | — | — | US | disclosed |
| US-20070232719-A1 | POLYMERIZABLE BICYCLIC CYCLOPROPANE DERIVATIVES AND THEIR USE FOR THE PREPARATION OF DENTAL MATERIALS | IVOCLAR VIVADENT AG (LI) | 2007-10-04 | — | — | US | disclosed |
| EP-1413569-B1 | Bicyclic cyclopropane derivatives capable of polymerisation and their use in the preparation of dental materials | IVOCLAR VIVADENT AG (LI) | 2006-12-13 | — | — | EP | disclosed |
| US-20060178469-A1 | Polymerizable cyclopropyl acrylates | IVOCLAR VIVADENT AG | 2006-08-10 | — | — | US | disclosed |
| EP-1688125-A1 | Polymerisable cyclopropylacrylates | Ivoclar Vivadent AG (LI) | 2006-08-09 | — | — | EP | disclosed |
| EP-1413569-A1 | Bicyclic cyclopropane derivatives capable of polymerisation and their use in the preparation of dental materials | Ivoclar Vivadent AG (LI) | 2004-04-28 | — | — | EP | disclosed |
| US-20040077882-A1 | Polymerizable bicyclic cyclopropane derivatives and their use for the preparation of dental materials | IVOCLAR VIVADENT AG (LI) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232719-A1 | POLYMERIZABLE BICYCLIC CYCLOPROPANE DERIVATIVES AND THEIR USE FOR THE PREPARATION OF DENTAL MATERIALS | CBR1, CYP8B1, OXER1 | ALDH1A1 2773/4885CYP1A2 89/4885CYP3A4 179/4885 |
| US-20180036209-A1 | Dental Materials Based on Monofunctional Vinylcyclopropane Derivatives | HVCN1, RAD51, HYOU1 | ALDH1A1 1243/4885CYP1A2 1037/4885CYP3A4 2318/4885 |
| US-20200087329-A1 | Acyl Germanium Photoinitiators And Process For The Preparation Thereof | AGPAT5, AGPAT2, GLRA2 | ALDH1A1 1349/4885CYP1A2 516/4885CYP3A4 109/4885 |
| US-20190167533-A1 | DENTAL MATERIALS BASED ON URETHANE-GROUP-CONTAINING VINYLCYCLOPROPANE DERIVATIVES | RAD51, CBR1, DECR1 | ALDH1A1 1734/4885CYP1A2 436/4885CYP3A4 1216/4885 |
| US-20040077882-A1 | Polymerizable bicyclic cyclopropane derivatives and their use for the preparation of dental materials | SCO2, CBR1, CORO1C | ALDH1A1 1884/4885CYP1A2 132/4885CYP3A4 306/4885 |
| US-11142592-B2 | Polymerizable compositions with acyltin photoinitiators | AGPAT2, AGPAT5, MBOAT1 | ALDH1A1 1039/4885CYP1A2 1347/4885CYP3A4 1912/4885 |
| US-10787468-B2 | Acyl germanium photoinitiators and process for the preparation thereof | AGPAT5, AGPAT2, GLRA2 | ALDH1A1 1349/4885CYP1A2 516/4885CYP3A4 109/4885 |
| US-11135136-B2 | Dental materials based on urethane-group-containing vinylcyclopropane derivatives | RAD51, CBR1, DECR1 | ALDH1A1 1734/4885CYP1A2 436/4885CYP3A4 1216/4885 |
| US-20060178469-A1 | Polymerizable cyclopropyl acrylates | CBR3, CBR1, ACAD9 | ALDH1A1 2762/4885CYP1A2 434/4885CYP3A4 1394/4885 |
| US-10660825-B2 | — | OXER1, CBR1, RAD51 | ALDH1A1 2341/4885CYP1A2 125/4885CYP3A4 782/4885 |
| US-20230322820-A1 | BISACYL DIGERMANIUM COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PHOTOINITIATOR FOR RADICAL POLYMERIZATION | GLRA3, GLRA2, CBR3 | ALDH1A1 765/4885CYP1A2 406/4885CYP3A4 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.