Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930728 | 0.75 | MAPT (0.59) | MAPTSMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL13929302 | 0.63 | TSHR (0.52) | MAPTSMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL13930735 | 0.57 | OPRM1 (0.47) | MAPTTP53POLB | |
| SCHEMBL13930847 | 0.57 | OPRM1 (0.47) | MAPTTP53POLB | |
| SCHEMBL30381367 | 0.56 | PKM (0.60) | MAPTSMN1; SMN2KMT2AMEN1TP53 | |
| SCHEMBL5226832 | 0.56 | PKM (0.60) | MAPTSMN1; SMN2KMT2AMEN1TP53 | |
| Hydrochloric Acid SCHEMBL9395861 | 0.55 | RAB9A (0.59) | MAPTSMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL18826081 | 0.55 | RAB9A (0.74) | SMN1; SMN2KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL8276267 | 0.55 | HTT (0.71) | MAPTSMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL31252414 | 0.55 | RAB9A (0.74) | SMN1; SMN2KMT2AMEN1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048291-A1 | Novel Piperidine-4-Acetic Acid Derivatives and Their Use | EUROSCREEN S.A. (BE) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048291-A1 | Novel Piperidine-4-Acetic Acid Derivatives and Their Use | ALDH1A1, ABAT, ALDH18A1 | MAPT 2479/4885SMN1; SMN2 2750/4885KMT2A 2340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.