Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | AGXT | P21549 | 2/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13863241 | 0.80 | CA9 (0.48) | CES2CES1ALDH1A1CA3CA6 | |
| SCHEMBL12330287 | 0.78 | ESR2 (0.53) | CA9 | |
| SCHEMBL7097753 | 0.76 | PPARG (0.38) | ALDH1A1TDP1ALOX12KMT2A | |
| SCHEMBL14140533 | 0.76 | NFE2L2 (0.36) | ALDH1A1TDP1NFE2L2CYP1A2CYP2A6 | |
| SCHEMBL17366292 | 0.76 | MAP2K2 (0.33) | — | |
| SCHEMBL14566097 | 0.75 | ALDH1A1 (0.42) | CES2CES1ALDH1A1CA3CA6 | |
| SCHEMBL20139015 | 0.74 | CA3 (0.52) | CES2CES1ALDH1A1CA3CA6 | |
| SCHEMBL25599762 | 0.73 | CA3 (0.46) | CES2CES1ALDH1A1CA3CA6 | |
| SCHEMBL15702941 | 0.73 | CA3 (0.32) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL21731047 | 0.72 | KDM4E (0.39) | CA9CA14NFE2L2HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611174-B1 | [1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE DERIVATIVE AS A2A RECEPTOR INHIBITOR | MEDSHINE DISCOVERY INC (CN) | 2022-06-08 | — | — | EP | disclosed |
| EP-3985005-A1 | FUSED RING COMPOUND AS FGFR AND VEGFR DUAL INHIBITOR | Medshine Discovery Inc. (CN) | 2022-04-20 | — | — | EP | disclosed |
| EP-3664802-B1 | BICYCLIC INHIBITORS OF HISTONE DEACETYLASE | ALKERMES INC (US) | 2022-02-23 | — | — | EP | disclosed |
| EP-3568135-B1 | BICYCLIC INHIBITORS OF HISTONE DEACETYLASE | ALKERMES INC (US) | 2021-04-07 | — | — | EP | disclosed |
| WO-2021018047-A1 | PYRIDINE DERIVATIVE AS FGFR AND VEGFR DUAL INHIBITORS | 南京明德新药研发有限公司 | 2021-02-04 | — | — | WO | disclosed |
| WO-2020249096-A1 | FUSED RING COMPOUND AS FGFR AND VEGFR DUAL INHIBITOR | 南京明德新药研发有限公司 | 2020-12-17 | — | — | WO | disclosed |
| EP-3611174-A1 | [1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE DERIVATIVE AS A2A RECEPTOR INHIBITOR | Medshine Discovery Inc. (CN) | 2020-02-19 | — | — | EP | disclosed |
| WO-2019032528-A1 | BICYCLIC INHIBITORS OF HISTONE DEACETYLASE | RODIN THERAPEUTICS, INC (US) | 2019-02-14 | — | — | WO | disclosed |
| WO-2018132533-A1 | BICYCLIC INHIBITORS OF HISTONE DEACETYLASE | RODIN THERAPEUTICS, INC. (US) | 2018-07-19 | — | — | WO | disclosed |
| WO-2018132531-A1 | BICYCLIC INHIBITORS OF HISTONE DEACETYLASE | RODIN THERAPEUTICS, INC. (US) | 2018-07-19 | — | — | WO | disclosed |
| US-8329897-B2 | Synthesis of inhibitors of 11β-hydroxysteroid dehydrogenase type 1 | VITAE PHARMACEUTICALS, INC. (US) | 2012-12-11 | — | — | US | disclosed |
| US-20100256363-A1 | SYNTHESIS OF INHIBITORS OF 11ß-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | VITAE PHARMACEUTICALS, INC. | 2010-10-07 | — | — | US | disclosed |
| US-7575817-B2 | Cyclometalated transition metal complex and organic electroluminescent device using the same | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2009-08-18 | — | — | US | disclosed |
| EP-1670757-B1 | PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | LILLY CO ELI (US) | 2009-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256363-A1 | SYNTHESIS OF INHIBITORS OF 11ß-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | HSD11B1, HSD11B2, HSD17B1 | CES2 814/4885CES1 44/4885ALDH1A1 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.