Codeinone

Codeinone

SCHEMBL13952981

COc1ccc2c3c1OC1C(=O)C=CC4C(C2)N(C)CC[C@]314

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 14/20 1.00
OPRK1 P41145 9/20 0.69
OPRD1 P41143 5/20 0.69
MRGPRX2 Q96LB1 4/20 0.66
PDE4D Q08499 2/20 0.66
ADRB1 P08588 1/20 0.66
PDE3A Q14432 1/20 0.66
LMNA P02545 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Codeinone SCHEMBL101725 1.00 OPRM1 (1.00) OPRM1OPRK1OPRD1MRGPRX2PDE4D
Codeinone SCHEMBL13633530 1.00 OPRM1 (1.00) OPRM1OPRK1OPRD1MRGPRX2PDE4D
Codeinone SCHEMBL13154678 1.00 OPRM1 (1.00) OPRM1OPRK1OPRD1MRGPRX2PDE4D
Codeinone SCHEMBL12137788 1.00 OPRM1 (1.00) OPRM1OPRK1OPRD1MRGPRX2PDE4D
Codeinone SCHEMBL100655 1.00 OPRM1 (1.00) OPRM1OPRK1OPRD1MRGPRX2PDE4D
Codeinone SCHEMBL14192923 1.00 OPRM1 (1.00) OPRM1OPRK1OPRD1MRGPRX2PDE4D
Codeinone SCHEMBL3107493 1.00 OPRM1 (1.00) OPRM1OPRK1OPRD1MRGPRX2PDE4D
Codeinone SCHEMBL29375985 1.00 OPRM1 (1.00) OPRM1OPRK1OPRD1MRGPRX2PDE4D
Codeinone SCHEMBL7707098 0.99 OPRM1 (0.98) OPRM1OPRK1OPRD1MRGPRX2PDE4D
Codeinone SCHEMBL11533410 0.95 OPRM1 (0.91) OPRM1OPRK1OPRD1MRGPRX2PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090053764-A1 Salutaridinol 7-0-Acetyltransferase and Derivatives Thereof DONALD DANFORTH PLANT SCIENCE CENTER (US) 2009-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090053764-A1 Salutaridinol 7-0-Acetyltransferase and Derivatives Thereof NAT10, RNGTT, RNMT OPRM1 765/4885OPRK1 1530/4885OPRD1 603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.