SCHEMBL13965624

SCHEMBL13965624

NCC1CNCC(n2cnc3c(NC(=O)c4ccccc4)ncnc32)O1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PRMT6 Q96LA8 1/20 0.44
P2RY12 Q9H244 2/20 0.43
ABL1 P00519 3/20 0.42
RIN1 Q13671 3/20 0.42
BMPR1B O00238 1/20 0.42
ADORA1 P30542 3/20 0.42
ADORA3 P0DMS8 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA2B P29275 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25764318 0.91 BMPR1B (0.44) PRMT6P2RY12BMPR1BADORA1
SCHEMBL19146448 0.89 CYP1A2 (0.48) PRMT6P2RY12ABL1RIN1
SCHEMBL19953997 0.83 PRMT6 (0.43) PRMT6P2RY12ABL1RIN1
SCHEMBL23379924 0.82 BMPR1B (0.41) PRMT6P2RY12BMPR1BADORA1ADORA3
SCHEMBL19343832 0.82 ABL1 (0.56) ABL1RIN1
SCHEMBL25004 0.82 ABL1 (0.56) ABL1RIN1
SCHEMBL9342988 0.81 SLC29A1 (0.49) PRMT6P2RY12ADORA3
SCHEMBL9342970 0.81 SLC29A1 (0.49) PRMT6P2RY12ADORA3
SCHEMBL14999606 0.79 P2RY12 (0.41) PRMT6P2RY12
SCHEMBL19146385 0.79 CYP1A2 (0.44) PRMT6P2RY12ABL1RIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120296087-A1 MORPHOLINO-BASED ANTISENSE AGENT INDIAN ASSOCIATION FOR THE CULTIVATION OF SCIENCE (IN) 2012-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120296087-A1 MORPHOLINO-BASED ANTISENSE AGENT MYOF, OSBP2, SLCO2B1 PRMT6 4002/4885P2RY12 554/4885ABL1 4099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.