Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397097 | 0.89 | GRM6 (0.34) | GRM6TP53RAB9AHSD17B10KDM4E | |
| SCHEMBL1397018 | 0.89 | ALDH1A1 (0.36) | GRM6TP53RAB9AHSD17B10KDM4E | |
| SCHEMBL3455010 | 0.88 | GRM6 (0.34) | GRM6TP53RAB9AHSD17B10KDM4E | |
| SCHEMBL679235 | 0.87 | GRM6 (0.37) | GRM6TP53RAB9AHSD17B10KDM4E | |
| SCHEMBL1397109 | 0.85 | ALDH1A1 (0.41) | HSD17B10KDM4EKLKB1ALDH1A1HTT | |
| SCHEMBL1397168 | 0.84 | PRKCZ (0.41) | RAB9AHSD17B10KDM4EMAPTNPC1 | |
| SCHEMBL1115136 | 0.83 | KDM4E (0.39) | HSD17B10KDM4EALDH1A1SMN1; SMN2DHPS | |
| SCHEMBL30151443 | 0.83 | KDM4E (0.39) | HSD17B10KDM4EALDH1A1SMN1; SMN2DHPS | |
| SCHEMBL1397107 | 0.83 | PRKCZ (0.37) | GRM6TP53RAB9AHSD17B10KDM4E | |
| SCHEMBL694313 | 0.82 | KLKB1 (0.38) | HSD17B10KDM4EKLKB1ALDH1A1DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8609592-B2 | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-12-17 | — | — | US | claimed |
| US-8609592-B2 | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-12-17 | — | — | US | disclosed |
| US-8426591-B2 | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-8426591-B2 | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-8426591-B2 | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-20130096005-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-04-18 | — | — | US | disclosed |
| US-20130096005-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-04-18 | — | — | US | disclosed |
| US-20130096005-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-04-18 | — | — | US | disclosed |
| EP-2181098-B1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2011-03-02 | — | — | EP | disclosed |
| US-20100121058-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-05-13 | — | — | US | disclosed |
| US-20100121058-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-05-13 | — | — | US | disclosed |
| EP-2181098-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2010-05-05 | — | — | EP | disclosed |
| US-7642220-B2 | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642220-B2 | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642220-B2 | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2010-01-05 | — | — | US | disclosed |
| WO-2009029735-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-03-05 | — | — | WO | disclosed |
| WO-2009029735-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-03-05 | — | — | WO | disclosed |
| US-20090062125-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC | 2009-03-05 | — | — | US | disclosed |
| US-20090062125-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC | 2009-03-05 | — | — | US | disclosed |
| US-20090062125-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096005-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, AADAC | GRM6 92/4885TP53 2898/4885RAB9A 3126/4885 |
| US-20100121058-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, AADAC | GRM6 92/4885TP53 2898/4885RAB9A 3126/4885 |
| US-20090062125-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, AADAC | GRM6 92/4885TP53 2898/4885RAB9A 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.