Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | DHPS | P49366 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 2/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30151443 | 1.00 | KDM4E (0.39) | KDM4EPKMRCE1TAS1R3TAS1R1 | |
| SCHEMBL1223170 | 0.93 | KDM4E (0.39) | KDM4EPKMRCE1TAS1R3TAS1R1 | |
| SCHEMBL29769728 | 0.92 | KDM4E (0.38) | KDM4EPKMRCE1TAS1R3TAS1R1 | |
| SCHEMBL16047411 | 0.92 | KDM4E (0.38) | KDM4EPKMRCE1TAS1R3TAS1R1 | |
| SCHEMBL679753 | 0.92 | KDM4E (0.38) | KDM4EPKMRCE1TAS1R3TAS1R1 | |
| SCHEMBL15226183 | 0.91 | TAS1R3 (0.37) | KDM4EPKMRCE1TAS1R3TAS1R1 | |
| SCHEMBL1918080 | 0.91 | KDM4E (0.37) | KDM4EPKMRCE1TAS1R3TAS1R1 | |
| SCHEMBL1222941 | 0.91 | MEP1B (0.39) | KDM4EPKMRCE1TAS1R3TAS1R1 | |
| SCHEMBL16044729 | 0.91 | KDM4E (0.37) | KDM4EPKMRCE1TAS1R3TAS1R1 | |
| SCHEMBL16076578 | 0.90 | KDM4E (0.37) | KDM4EPKMRCE1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9763447-B2 | Safening 6-amino-2-(substituted phenyl)-5-substituted-4-pyrimidinecarboxylate herbicide injury on cereal crops | DOW AGROSCIENCES LLC (US) | 2017-09-19 | — | — | US | claimed |
| US-20160316745-A1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4- PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | CORTEVA AGRISCIENCE LLC | 2016-11-03 | — | — | US | claimed |
| US-9408387-B2 | Safening 6-amino-2-(substituted phenyl)-5-substituted-4-pyrimidinecarboxylate herbicide injury on cereal crops | DOW AGROSCIENCES LLC (US) | 2016-08-09 | — | — | US | claimed |
| EP-2493292-B1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | DOW AGROSCIENCES LLC (US) | 2016-05-18 | — | — | EP | claimed |
| US-8609592-B2 | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-12-17 | — | — | US | claimed |
| EP-3458442-B1 | SYNTHESIS OF 6-ARYL-4-AMINOPICOLINATES AND 2-ARYL-6-AMINOPYRIMIDINE-4-CARBOXYLATES BY DIRECT SUZUKI COUPLING | CORTEVA AGRISCIENCE LLC (US) | 2022-12-28 | — | — | EP | disclosed |
| US-10570114-B2 | Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct suzuki coupling | DOW AGROSCIENCES LLC (US) | 2020-02-25 | — | — | US | disclosed |
| US-10544121-B2 | Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct suzuki coupling | DOW AGROSCIENCES LLC (US) | 2020-01-28 | — | — | US | disclosed |
| EP-3458442-A1 | SYNTHESIS OF 6-ARYL-4-AMINOPICOLINATES AND 2-ARYL-6-AMINOPYRIMIDINE-4-CARBOXYLATES BY DIRECT SUZUKI COUPLING | Dow Agrosciences LLC (US) | 2019-03-27 | — | — | EP | disclosed |
| US-20180334445-A1 | SYNTHESIS OF 6-ARYL-4-AMINOPICOLINATES AND 2-ARYL-6-AMINOPYRIMIDINE-4-CARBOXYLATES BY DIRECT SUZUKI COUPLING | DOW AGROSCIENCES LLC (US) | 2018-11-22 | — | — | US | disclosed |
| US-20180334444-A1 | SYNTHESIS OF 6-ARYL-4-AMINOPICOLINATES AND 2-ARYL-6-AMINOPYRIMIDINE-4-CARBOXYLATES BY DIRECT SUZUKI COUPLING | DOW AGROSCIENCES LLC (US) | 2018-11-22 | — | — | US | disclosed |
| US-10087164-B2 | Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct Suzuki coupling | DOW AGROSCIENCES LLC (US) | 2018-10-02 | — | — | US | disclosed |
| US-7642220-B2 | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2010-01-05 | — | — | US | disclosed |
| WO-2009129291-A1 | 2-(SUBSTITUTED PHENYL)-6-HYDROXY OR ALKOXY-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-10-22 | — | — | WO | disclosed |
| US-20090264293-A1 | 2-(SUBSTITUTED PHENYL)-6-HYDROXY OR ALKOXY-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-10-22 | — | — | US | disclosed |
| US-20090062125-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC | 2009-03-05 | — | — | US | disclosed |
| US-20090062125-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC | 2009-03-05 | — | — | US | disclosed |
| WO-2009029735-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-03-05 | — | — | WO | disclosed |
| US-20090062125-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC | 2009-03-05 | — | — | US | disclosed |
| WO-2009029735-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570114-B2 | Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct suzuki coupling | DDC, AAAS, AASDHPPT | KDM4E 12/4885PKM 1750/4885RCE1 751/4885 |
| US-20090264293-A1 | 2-(SUBSTITUTED PHENYL)-6-HYDROXY OR ALKOXY-5-SUBSTITUTED-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, HPD, DDC | KDM4E 328/4885PKM 1471/4885RCE1 1971/4885 |
| US-20180334444-A1 | SYNTHESIS OF 6-ARYL-4-AMINOPICOLINATES AND 2-ARYL-6-AMINOPYRIMIDINE-4-CARBOXYLATES BY DIRECT SUZUKI COUPLING | DDC, AAAS, AASDHPPT | KDM4E 12/4885PKM 1750/4885RCE1 751/4885 |
| US-10087164-B2 | Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct Suzuki coupling | DDC, AAAS, AASDHPPT | KDM4E 12/4885PKM 1835/4885RCE1 731/4885 |
| US-20180334445-A1 | SYNTHESIS OF 6-ARYL-4-AMINOPICOLINATES AND 2-ARYL-6-AMINOPYRIMIDINE-4-CARBOXYLATES BY DIRECT SUZUKI COUPLING | DDC, AAAS, AASDHPPT | KDM4E 12/4885PKM 1750/4885RCE1 751/4885 |
| US-20160316745-A1 | SAFENING 6-AMINO-2-(SUBSTITUTED PHENYL)-5-SUBSTITUTED-4- PYRIMIDINECARBOXYLATE HERBICIDE INJURY ON CEREAL CROPS | CASP6, CASP2, DHFR | KDM4E 1445/4885PKM 1211/4885RCE1 627/4885 |
| US-20090062125-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, AADAC | KDM4E 381/4885PKM 1532/4885RCE1 2524/4885 |
| US-10544121-B2 | Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct suzuki coupling | DDC, AAAS, AASDHPPT | KDM4E 12/4885PKM 1750/4885RCE1 751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.