Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113773 | 0.81 | HDAC6 (0.46) | CYP1A2CYP2C19HDAC1HDAC3HDAC7 | |
| SCHEMBL9815030 | 0.79 | EP300 (0.60) | CYP1A2CYP2C19HDAC1HDAC3HDAC7 | |
| SCHEMBL9815026 | 0.78 | ALDH1A1 (0.51) | CYP1A2CYP2C19HDAC1HDAC3HDAC7 | |
| SCHEMBL10113508 | 0.76 | HDAC6 (0.46) | CYP1A2CYP2C19HDAC1HDAC3HDAC7 | |
| SCHEMBL9815029 | 0.75 | ALDH1A1 (0.54) | CYP1A2CYP2C19HDAC1HDAC3HDAC7 | |
| SCHEMBL5907677 | 0.74 | SMN1; SMN2 (0.50) | CYP1A2CYP2C19HDAC1HDAC7HDAC8 | |
| SCHEMBL9815043 | 0.73 | CYP1A2 (0.57) | CYP1A2CYP2C19HDAC1HDAC7HDAC8 | |
| SCHEMBL8613334 | 0.73 | HDAC1 (0.51) | HDAC1HDAC3HDAC7HDAC8HDAC6 | |
| SCHEMBL8579316 | 0.73 | TERT (0.57) | CYP1A2CYP2C19HDAC1HDAC3HDAC7 | |
| SCHEMBL776746 | 0.70 | LMNA (0.60) | HDAC1HDAC3HDAC7HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |