Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397763 | 0.95 | C5AR1 (0.32) | C5AR1F2F10F7FFAR4 | |
| SCHEMBL1397672 | 0.91 | EEF2K (0.30) | — | |
| SCHEMBL1397708 | 0.88 | — | — | |
| SCHEMBL1397670 | 0.88 | ALDH1A1 (0.31) | — | |
| SCHEMBL1397699 | 0.86 | C5AR1 (0.31) | C5AR1 | |
| SCHEMBL1397598 | 0.83 | GRIN2B (0.31) | C5AR1 | |
| SCHEMBL1397657 | 0.81 | CENPE (0.30) | — | |
| SCHEMBL1397692 | 0.80 | NLRP3 (0.31) | C5AR1FFAR4 | |
| SCHEMBL1397700 | 0.78 | MCL1 (0.31) | — | |
| SCHEMBL1397674 | 0.77 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007726-B1 | BENZAMIDE AND HETEROARENE DERIVATIVES AS CETP INHIBITORS | HOFFMANN LA ROCHE (CH) | 2011-03-02 | — | — | EP | disclosed |