Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 13/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL862362 | 0.77 | ELANE (0.47) | ELANEPARP1 | |
| SCHEMBL12130977 | 0.72 | KDM4E (0.42) | LMNA | |
| SCHEMBL30667298 | 0.67 | ELANE (0.44) | ELANEPARP1 | |
| SCHEMBL30022899 | 0.66 | CYP3A4 (0.43) | LMNA | |
| SCHEMBL1537728 | 0.66 | CYP3A4 (0.43) | LMNA | |
| SCHEMBL10147922 | 0.66 | ACHE (0.46) | ELANEPARP1LMNA | |
| SCHEMBL12130979 | 0.66 | KDM4C (0.41) | — | |
| SCHEMBL8404515 | 0.65 | ELANE (0.50) | ELANEPARP1 | |
| SCHEMBL460290 | 0.64 | GPR3 (0.57) | ELANEPARP1 | |
| SCHEMBL19503506 | 0.63 | PTGES (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005371-A1 | Substituted Fused [1,2]Imidazo[4,5-C] Ring Compounds and Methods | 3M INNOVATIVE PROPERTIES COMPANY | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005371-A1 | Substituted Fused [1,2]Imidazo[4,5-C] Ring Compounds and Methods | IL2, IFNG, IL4 | ELANE 1518/4885PARP1 3051/4885LMNA 2548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.