Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 6/20 | 0.41 |
| ▸ | MAOA | P21397 | 6/20 | 0.41 |
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 6/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770593 | 0.90 | MAPT (0.41) | LMNAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL1663443 | 0.81 | KMT2A (0.46) | LMNAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL1665243 | 0.78 | MAPT (0.48) | LMNAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL8769706 | 0.78 | RAB9A (0.58) | LMNAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL21254928 | 0.75 | RAB9A (0.55) | LMNAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL1665074 | 0.75 | RAB9A (0.52) | LMNAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL1664007 | 0.74 | RAB9A (0.51) | LMNAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL1665239 | 0.74 | SMN1; SMN2 (0.46) | LMNAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL1664031 | 0.73 | ALDH1A1 (0.48) | LMNAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL1663295 | 0.73 | HPGDS (0.63) | LMNANPC1RAB9AMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295904-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295904-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | MPL, CSF3R, HGF | LMNA 3995/4885ALDH1A1 2736/4885NPC1 4555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.