SCHEMBL744661

SCHEMBL744661

Cc1ccc(C(=O)C(C)C(=O)c2ccccc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.63
CES1 P23141 2/20 0.63
NPC1 O15118 3/20 0.57
RAB9A P51151 3/20 0.57
KMT2A Q03164 2/20 0.57
MEN1 O00255 1/20 0.57
SMN1; SMN2 Q16637 5/20 0.52
ALDH1A1 P00352 3/20 0.52
LMNA P02545 5/20 0.52
POLB P06746 1/20 0.52
KDM4E B2RXH2 2/20 0.50
VCP P55072 1/20 0.50
HTT P42858 1/20 0.50
MAPT P10636 3/20 0.48
AKR1C3 P42330 1/20 0.48
TDP1 Q9NUW8 2/20 0.47
PGR P06401 1/20 0.47
ADRA2A P08913 1/20 0.47
ADRA2B P18089 1/20 0.47
HTR2A P28223 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10577256 0.91 ALDH1A1 (0.56) CES2CES1NPC1RAB9AKMT2A
SCHEMBL1397470 0.89 KMT2A (0.58) CES2CES1NPC1RAB9AKMT2A
SCHEMBL7028909 0.85 ALDH1A1 (0.54) CES2CES1NPC1RAB9AKMT2A
SCHEMBL7867720 0.83 CES2 (0.59) CES2CES1RAB9AKMT2AMEN1
SCHEMBL19520246 0.83 ALDH1A1 (0.52) CES2CES1NPC1RAB9AKMT2A
SCHEMBL29589199 0.82 SMN1; SMN2 (0.56) NPC1RAB9AKMT2AMEN1SMN1; SMN2
SCHEMBL28043394 0.82 NPC1 (0.53) CES2CES1NPC1RAB9AKMT2A
SCHEMBL27493547 0.82 CES2 (0.61) CES2CES1KMT2AMEN1SMN1; SMN2
SCHEMBL4971852 0.82 CYP2C9 (0.52) CES2CES1NPC1RAB9AKMT2A
SCHEMBL28043313 0.82 SMN1; SMN2 (0.53) CES2CES1NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4395733-A1 A PHOTOPROTECTIVE PERSONAL CARE COMPOSITION Unilever IP Holdings B.V. (NL) 2024-07-10 EP claimed
WO-2023030963-A1 A PHOTOPROTECTIVE PERSONAL CARE COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2023-03-09 WO claimed
US-10952944-B2 Cyclocarboxylic acid containing personal care compositions CONOPCO, INC. (US) 2021-03-23 US claimed
EP-3373899-B1 CYCLOCARBOXYLIC ACID CONTAINING PERSONAL CARE COMPOSITIONS UNILEVER PLC (GB) 2019-09-18 EP claimed
US-20190183767-A1 Sunscreen Compositions KOBO PRODUCTS, INC. (US) 2019-06-20 US claimed
EP-3463259-A1 SUNSCREEN COMPOSITIONS Kobo Products Inc. (US) 2019-04-10 EP claimed
US-20180318190-A1 CYCLOCARBOXYLIC ACID CONTAINING PERSONAL CARE COMPOSITIONS CONOPCO, INC., D/B/A UNILEVER (US) 2018-11-08 US claimed
EP-3373899-A1 CYCLOCARBOXYLIC ACID CONTAINING PERSONAL CARE COMPOSITIONS Unilever Plc. (GB) 2018-09-19 EP claimed
EP-2575748-B1 SUNSCREEN COMPOSITION UNILEVER NV (NL) 2018-04-11 EP claimed
WO-2017210406-A1 SUNSCREEN COMPOSITIONS KOBO PRODUCTS, INC. (US) 2017-12-07 WO claimed
CN-101505717-A Photostable cosmetic compositions UNILEVER NV (NL) 2009-08-12 CN claimed
EP-2054017-A1 PHOTOSTABLE COSMETIC COMPOSITIONS Unilever PLC (GB) 2009-05-06 EP claimed
US-20080050322-A1 Photostable cosmetic compositions CONOPCO INC, D/B/A UNILEVER 2008-02-28 US claimed
WO-2008022946-A1 PHOTOSTABLE COSMETIC COMPOSITIONS UNILEVER PLC (GB) 2008-02-28 WO claimed
EP-1181000-B1 A METHOD FOR OBTAINING PHOTOSTABLE SUNSCREEN COMPOSITIONS SOL GEL TECHNOLOGIES LTD (IL) 2007-02-07 EP claimed
CN-1154472-C Light screening composition - 2004-06-23 CN claimed
US-6436375-B1 ENCAPSULATION OF DIFFERENT ACTIVE INGREDIENTS (WHICH ARE PHOTODEGRADED WHEN PRESENT TOGETHER) IN SEPARATE MICROCAPSULES SOL-GEL TECHNOLOGIES LTD. (IL) 2002-08-20 US claimed
EP-1181000-A1 A METHOD FOR OBTAINING PHOTOSTABLE SUNSCREEN COMPOSITIONS Sol-Gel Technologies Ltd. (IL) 2002-02-27 EP claimed
WO-2000071084-A1 A METHOD FOR OBTAINING PHOTOSTABLE SUNSCREEN COMPOSITIONS SOL-GEL TECHNOLOGIES LTD (IL) 2000-11-30 WO claimed
US-5985251-A DIBENZOYLMETHANE DERIVATIVE, 3,3-DIPHENYLACRYLATE- OR BENZYLIDENE CAMPHOR DERIVATIVE, P-METHOXYCINNAMATE DERIVATIVE, ROCHE VITAMINS INC. (US) 1999-11-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180318190-A1 CYCLOCARBOXYLIC ACID CONTAINING PERSONAL CARE COMPOSITIONS ERCC1, C1R, COL1A1 CES2 3063/4885CES1 726/4885NPC1 2952/4885
US-10952944-B2 Cyclocarboxylic acid containing personal care compositions ERCC1, C1R, COL1A1 CES2 3063/4885CES1 726/4885NPC1 2952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.