Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.49 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.49 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397470 | 0.87 | KMT2A (0.58) | SMN1; SMN2LMNAALDH1A1KMT2ANPC1 | |
| SCHEMBL5889317 | 0.86 | CES2 (0.48) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL7867720 | 0.82 | CES2 (0.59) | SMN1; SMN2LMNAKMT2AMEN1RAB9A | |
| SCHEMBL744661 | 0.82 | CES2 (0.63) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL847200 | 0.81 | LMNA (0.58) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL28956876 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL4971852 | 0.80 | CYP2C9 (0.52) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL27493547 | 0.80 | CES2 (0.61) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL28043394 | 0.80 | NPC1 (0.53) | SMN1; SMN2LMNAKMT2AMEN1NPC1 | |
| SCHEMBL28180008 | 0.79 | RAB9A (0.68) | LMNAALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105254483-A | Method for preparing 2-methyl-1,3-dicarbonyl derivative | UNIV SOOCHOW | 2016-01-20 | — | — | CN | disclosed |