SCHEMBL1397474

SCHEMBL1397474

COC(=O)/C=C/c1ccccc1OC

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 2/20 0.75
TFEB P19484 1/20 0.74
KDM4E B2RXH2 5/20 0.72
MAPT P10636 5/20 0.66
NPC1 O15118 3/20 0.66
RAB9A P51151 2/20 0.66
LMNA P02545 2/20 0.66
BCHE P06276 1/20 0.66
MAPK1 P28482 2/20 0.64
ATM Q13315 1/20 0.64
NPSR1 Q6W5P4 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
LY96 Q9Y6Y9 1/20 0.62
MAOB P27338 3/20 0.60
AR P10275 1/20 0.60
HPGD P15428 5/20 0.59
ALDH1A1 P00352 4/20 0.59
KMT2A Q03164 2/20 0.59
CYP1A2 P05177 3/20 0.59
CYP2D6 P10635 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6737719 1.00 NFE2L2 (0.75) NFE2L2TFEBKDM4EMAPTNPC1
SCHEMBL10438847 0.87 ALDH1A1 (0.58) NFE2L2TFEBKDM4EMAPTNPC1
SCHEMBL69522 0.87 ALDH1A1 (0.58) NFE2L2TFEBKDM4EMAPTNPC1
SCHEMBL5598849 0.86 NFE2L2 (1.00) NFE2L2TFEBKDM4EMAPTNPC1
SCHEMBL5598851 0.86 NFE2L2 (1.00) NFE2L2TFEBKDM4EMAPTNPC1
Cyclopropane SCHEMBL11842187 0.85 NFE2L2 (0.60) NFE2L2TFEBKDM4EMAPTNPC1
SCHEMBL2744047 0.85 NFE2L2 (1.00) NFE2L2TFEBKDM4EMAPTNPC1
SCHEMBL30307386 0.85 NFE2L2 (1.00) NFE2L2TFEBKDM4EMAPTNPC1
SCHEMBL2744044 0.85 NFE2L2 (1.00) NFE2L2TFEBKDM4EMAPTNPC1
SCHEMBL29805195 0.85 NFE2L2 (1.00) NFE2L2TFEBKDM4EMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119980263-A Sun-screening agent, sun-screening composition and preparation method of sun-screening agent 牛吉娜 2025-05-13 CN claimed
CN-117986487-A Modified polyglycolic acid raw material composition with improved compressive property, modified polyglycolic acid, preparation method and application thereof 中国石油化工股份有限公司 2024-05-07 CN claimed
CN-110540505-B Green and clean production process of isooctyl p-methoxycinnamate 安徽圣诺贝化学科技有限公司 2022-07-08 CN claimed
CN-110040833-B Preparation method of heavy metal ion trapping agent for electroplating wastewater 襄阳先创环保科技有限公司 2021-09-03 CN claimed
US-20080020004-A1 Hair-Treatment Agent Comprising Terpolymer Of Vinylpyrrolidone, Methacrylamide And Vinylimidazole And Active Ingredients And Additives WELLA AG (DE) 2008-01-24 US claimed
EP-1584323-B1 Use of N-hydroxyalkyl-O-benzylchitosans in hair treatment WELLA AG (DE) 2007-10-24 EP claimed
EP-1463482-A4 PHOTOSTABLE SUNSCREEN COMPOSITIONS AND METHODS OF STBAILIZING AVON PROD INC (US) 2005-03-16 EP claimed
EP-1463482-A1 PHOTOSTABLE SUNSCREEN COMPOSITIONS AND METHODS OF STBAILIZING AVON PRODUCTS, INC. (US) 2004-10-06 EP claimed
WO-2003051318-A1 PHOTOSTABLE SUNSCREEN COMPOSITIONS AND METHODS OF STBAILIZING AVON PRODUCTS, INC. (US) 2003-06-26 WO claimed
US-20260000076-A1 ANTIMICROBIAL COMBINATIONS CLARIANT INT LTD (CH) 2026-01-01 US disclosed
EP-4637352-A2 ANTIMICROBIAL COMBINATIONS CLARIANT INTERNATIONAL LTD (CH) 2025-10-29 EP disclosed
EP-4598500-A1 COMBINATION COMPRISING A GLUCAMIDE AND A CO-EMULSIFIER CLARIANT INTERNATIONAL LTD (CH) 2025-08-13 EP disclosed
EP-4245293-B1 USE OF SUGAR AMINES AS COMPLEXING AGENTS CLARIANT INT LTD (CH) 2025-08-06 EP disclosed
EP-4557953-A1 ANTIMICROBIAL COMBINATIONS CLARIANT INTERNATIONAL LTD (CH) 2025-05-28 EP disclosed
EP-0389434-A1 Bis(1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidin-4-yl)-amine Derivatives and Stabilized compositions CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed
EP-0389422-A2 Stabilizers derived from N-hydroxy hindered amines by Michael addition reactions CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed
EP-0389430-A1 N-hydrocarbyloxy hindered amine light stabilizers substituted with phosphorus moieties CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed
EP-0354234-A1 NEW AMINES, THEIR USE AND PREPARATION KabiVitrum AB (SE) 1990-02-14 EP disclosed
WO-1989006644-A1 NEW AMINES, THEIR USE AND PREPARATION KABIVITRUM AB (SE) 1989-07-27 WO disclosed
EP-0325571-A1 New amines, their use and preparation Kabi Pharmacia AB (SE) 1989-07-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260000076-A1 ANTIMICROBIAL COMBINATIONS FFAR1, ELOVL3, ACAD11 NFE2L2 1500/4885TFEB 2984/4885KDM4E 3135/4885
US-20080020004-A1 Hair-Treatment Agent Comprising Terpolymer Of Vinylpyrrolidone, Methacrylamide And Vinylimidazole And Active Ingredients And Additives PLOD3, POLR1C, PTMA NFE2L2 4676/4885TFEB 2572/4885KDM4E 1686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.