Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 4/20 | 0.33 |
| ▸ | CHUK | O15111 | 3/20 | 0.33 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | DHPS | P49366 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397826 | 0.94 | C5AR1 (0.35) | C5AR1IKBKBCHUKNR1I3CCR2 | |
| SCHEMBL1397409 | 0.91 | C5AR1 (0.38) | C5AR1IKBKBCHUKCYP2C19MEN1 | |
| SCHEMBL1397367 | 0.87 | TRPM8 (0.35) | C5AR1IKBKBCHUKNR1I3CYP2C19 | |
| SCHEMBL1397683 | 0.79 | MAPT (0.33) | IKBKBCHUKMAOBALDH1A1TP53 | |
| SCHEMBL1397674 | 0.79 | LMNA (0.33) | NR1I3MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL1397533 | 0.79 | TP53 (0.31) | NR1I3TP53MAPT | |
| SCHEMBL1397699 | 0.79 | C5AR1 (0.31) | C5AR1NR1I3 | |
| SCHEMBL1397640 | 0.78 | IKBKB (0.38) | C5AR1IKBKBCHUKMAOBMEN1 | |
| SCHEMBL1397662 | 0.78 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL1397697 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007726-B1 | BENZAMIDE AND HETEROARENE DERIVATIVES AS CETP INHIBITORS | HOFFMANN LA ROCHE (CH) | 2011-03-02 | — | — | EP | disclosed |