Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | KCNB1 | Q14721 | 4/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.36 |
| ▸ | Q9HBH1 | 1/20 | 0.36 | |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19445833 | 0.95 | KLKB1 (0.42) | KLKB1TSHRMMP2KCNB1HPGDS | |
| SCHEMBL12516946 | 0.95 | KLKB1 (0.42) | KLKB1TSHRMMP2KCNB1HPGDS | |
| SCHEMBL19445834 | 0.89 | MMP2 (0.39) | KLKB1TSHRMMP2KCNB1HPGDS | |
| SCHEMBL12779221 | 0.88 | ERAP2 (0.47) | KLKB1TSHRMMP2HPGDSERAP2 | |
| SCHEMBL19944963 | 0.86 | HPGDS (0.48) | KLKB1TSHRMMP2KCNB1HPGDS | |
| SCHEMBL10260677 | 0.84 | KLKB1 (0.41) | KLKB1TSHRMMP2KCNB1ERAP2 | |
| SCHEMBL19445719 | 0.84 | KLKB1 (0.41) | KLKB1TSHRMMP2KCNB1ERAP2 | |
| SCHEMBL19445498 | 0.84 | ROCK2 (0.39) | KLKB1TSHRMMP2KCNB1HDAC1 | |
| SCHEMBL10263520 | 0.84 | ERAP2 (0.43) | KLKB1TSHRMMP2KCNB1ERAP2 | |
| SCHEMBL21371588 | 0.84 | ROCK2 (0.39) | KLKB1TSHRMMP2KCNB1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012158672-A2 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | POLYMEDIX, INC. (US) | 2012-11-22 | — | — | WO | disclosed |