Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | UGCG | Q16739 | 1/20 | 0.32 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658709 | 0.86 | POLB (0.40) | MEN1KMT2ASMN1; SMN2P2RX1TP53 | |
| SCHEMBL298242 | 0.83 | P2RX1 (0.44) | HTTMEN1KMT2ASMN1; SMN2P2RX1 | |
| SCHEMBL13977480 | 0.83 | HTT (0.35) | HTTMEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL18156548 | 0.83 | SMN1; SMN2 (0.34) | HTTMEN1KMT2ASMN1; SMN2P2RX1 | |
| SCHEMBL12439454 | 0.82 | P2RX1 (0.38) | MEN1KMT2ASMN1; SMN2P2RX1ALDH1A1 | |
| SCHEMBL297702 | 0.79 | MAPT (0.54) | MEN1KMT2ASMN1; SMN2HSD17B10TP53 | |
| SCHEMBL14850235 | 0.78 | P2RX1 (0.46) | MEN1KMT2ASMN1; SMN2P2RX1MAPT | |
| SCHEMBL297830 | 0.78 | KDM4E (0.43) | HTTMEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL298535 | 0.78 | ALDH1A1 (0.40) | HTTMEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL14850246 | 0.78 | ALDH1A1 (0.42) | HTTMEN1KMT2ASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295907-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295907-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, BCHE | HTT 2212/4885MEN1 3134/4885KMT2A 1857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.