Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.37 |
| ▸ | USP1 | O94782 | 3/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14641589 | 0.75 | MET (0.49) | ACHE | |
| SCHEMBL13981975 | 0.73 | MET (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL14641595 | 0.68 | POLB (0.39) | — | |
| SCHEMBL14641757 | 0.63 | F10 (0.39) | — | |
| SCHEMBL14641623 | 0.62 | MET (0.42) | USP1HCRTR1HCRTR2 | |
| SCHEMBL14641587 | 0.62 | USP1 (0.41) | USP1 | |
| SCHEMBL14641598 | 0.61 | MET (0.57) | USP1 | |
| SCHEMBL1581704 | 0.61 | JAK2 (0.48) | — | |
| SCHEMBL18006543 | 0.61 | MAPT (0.48) | — | |
| SCHEMBL1581374 | 0.60 | MET (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008148449-A1 | 2-OXO-3-BENZYL-BENZOXAZOL-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS MET KINASE INHIBITORS FOR THE TREATMENT OF TUMORS | MERCK PATENT GMBH (DE) | 2008-12-11 | — | — | WO | disclosed |