Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13982690 | 0.81 | HPGD (0.47) | HPGDTDP1GPR35ALDH1A1MEN1 | |
| SCHEMBL13982718 | 0.81 | TSHR (0.55) | TDP1GPR35ALDH1A1MAPK1MAPT | |
| SCHEMBL2950121 | 0.80 | VCAM1 (0.50) | HPGDTDP1GPR35ALDH1A1MEN1 | |
| SCHEMBL21957846 | 0.80 | VCAM1 (0.50) | HPGDTDP1GPR35ALDH1A1MEN1 | |
| SCHEMBL13983232 | 0.78 | ALDH1A1 (0.42) | HPGDTDP1GPR35ALDH1A1MEN1 | |
| SCHEMBL11227718 | 0.77 | KCNH2 (0.41) | HPGDTDP1GPR35ALDH1A1MEN1 | |
| SCHEMBL11239984 | 0.76 | KCNH2 (0.43) | HPGDTDP1GPR35ALDH1A1MEN1 | |
| SCHEMBL11231321 | 0.76 | KCNH2 (0.43) | HPGDTDP1GPR35ALDH1A1MEN1 | |
| SCHEMBL21961905 | 0.75 | TDP1 (0.49) | HPGDTDP1GPR35ALDH1A1MEN1 | |
| SCHEMBL13983242 | 0.75 | ALDH1A1 (0.38) | HPGDTDP1GPR35ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156656-A2 | METHOD FOR MAKING BIARYL COMPOUNDS, COMPOUNDS MADE BY THE METHOD, AND METHOD FOR THEIR USE | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2008-12-24 | — | — | WO | disclosed |