Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13982751 | 0.82 | HPGD (0.39) | ALDH1A1LMNATDP1GPR35HPGD | |
| SCHEMBL13983237 | 0.81 | MAPK1 (0.40) | ALDH1A1LMNATDP1GPR35HPGD | |
| SCHEMBL20455632 | 0.81 | L3MBTL1 (0.37) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL13982723 | 0.78 | HPGD (0.45) | ALDH1A1TDP1GPR35HPGDMAPT | |
| SCHEMBL11452376 | 0.75 | HSD17B10 (0.43) | ALDH1A1TDP1GPR35HPGDMEN1 | |
| SCHEMBL13982690 | 0.74 | HPGD (0.47) | ALDH1A1TDP1GPR35HPGDMAPT | |
| SCHEMBL2950121 | 0.73 | VCAM1 (0.50) | ALDH1A1TDP1GPR35HPGDMAPT | |
| SCHEMBL21957846 | 0.73 | VCAM1 (0.50) | ALDH1A1TDP1GPR35HPGDMAPT | |
| SCHEMBL11451658 | 0.72 | ALDH1A1 (0.39) | ALDH1A1TDP1GPR35HPGDMAPT | |
| SCHEMBL13983242 | 0.70 | ALDH1A1 (0.38) | ALDH1A1LMNATDP1GPR35HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156656-A2 | METHOD FOR MAKING BIARYL COMPOUNDS, COMPOUNDS MADE BY THE METHOD, AND METHOD FOR THEIR USE | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2008-12-24 | — | — | WO | disclosed |