SCHEMBL13984232

SCHEMBL13984232

CC(C)(C)Cc1ccc(I)cc1CC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 2/20 0.33
IDO1 P14902 1/20 0.33
SLC6A4 P31645 3/20 0.33
SLC6A2 P23975 1/20 0.33
ESR1 P03372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6272172 0.81 KLF10 (0.40) SLC6A4SLC6A2ESR1
SCHEMBL13873011 0.81 IDO1 (0.50) RIPK1IDO1SLC6A4SLC6A2ESR1
SCHEMBL840263 0.74 TSHR (0.42) RIPK1ESR1
SCHEMBL1666375 0.74 CYP1A2 (0.37)
SCHEMBL841822 0.73 MEN1 (0.35) RIPK1SLC6A4ESR1
SCHEMBL26222585 0.70 ESR1 (0.37) RIPK1ESR1
SCHEMBL6685097 0.69 RIPK1 (0.56) RIPK1IDO1SLC6A2ESR1
SCHEMBL11955108 0.69 ESR1 (0.58) IDO1SLC6A4SLC6A2ESR1
SCHEMBL8104506 0.69 IDO1 (0.36) IDO1SLC6A4SLC6A2
SCHEMBL14651496 0.67 PKM (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed