SCHEMBL840263

SCHEMBL840263

CC(C)(C)Cc1ccc(N)cc1CC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
GAA P10253 2/20 0.42
MAPT P10636 2/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
PRKCI P41743 1/20 0.39
ACHE P22303 2/20 0.38
ALDH1A1 P00352 1/20 0.37
CASP1 P29466 3/20 0.36
RIPK1 Q13546 1/20 0.34
NR1H2 P55055 1/20 0.34
EPHX2 P34913 1/20 0.34
NR1H4 Q96RI1 1/20 0.34
CYP3A4 P08684 3/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
ESR1 P03372 1/20 0.33
PDE10A Q9Y233 1/20 0.33
GLA P06280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9833902 0.84 CASP1 (0.44) TSHRGAAMAPTMAPK1HTT
SCHEMBL18386492 0.82 ALDH1A1 (0.50) TSHRGAAMAPTMAPK1HTT
SCHEMBL17726213 0.80 ADRA2B (0.45) TSHRGAAMAPTMAPK1HTT
SCHEMBL24278774 0.80 PRKCI (0.36) TSHRGAAMAPTMAPK1HTT
SCHEMBL841822 0.74 MEN1 (0.35) TSHRGAAMAPTHTTALDH1A1
SCHEMBL13984232 0.74 RIPK1 (0.33) RIPK1ESR1
SCHEMBL23057561 0.74 DPP4 (0.41) TSHRMAPTMAPK1HTTALDH1A1
SCHEMBL18979299 0.71 ESR1 (0.43) TSHRGAAMAPTMAPK1HTT
SCHEMBL6685097 0.71 RIPK1 (0.56) HTTACHERIPK1ESR1
SCHEMBL395438 0.70 PRKCI (0.47) TSHRGAAMAPTMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C TSHR 4444/4885GAA 3715/4885MAPT 996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.