SCHEMBL841822

SCHEMBL841822

CC(C)(C)Cc1ccc(Br)cc1CC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HTT P42858 1/20 0.35
PYCR1 P32322 4/20 0.33
RIPK1 Q13546 1/20 0.33
NPY1R P25929 1/20 0.33
NPY2R P49146 1/20 0.33
KDM4E B2RXH2 2/20 0.32
ESR1 P03372 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
SLC6A4 P31645 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CCR5 P51681 1/20 0.31
GAA P10253 1/20 0.31
TSHR P16473 1/20 0.31
GFER P55789 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16787769 0.83 PYCR1 (0.45) MEN1KMT2AHTTPYCR1RIPK1
SCHEMBL6267782 0.81 TSHR (0.46) MEN1KMT2AHTTKDM4EESR1
SCHEMBL13020786 0.81 PYCR1 (0.46) PYCR1
SCHEMBL17185867 0.78 KDM1A (0.40) PYCR1SLC6A4PTGDR2
SCHEMBL6273175 0.78 KDM4E (0.51) MEN1KMT2AHTTKDM4EALDH1A1
SCHEMBL12672351 0.75 RIPK1 (0.38) RIPK1ESR1
SCHEMBL840263 0.74 TSHR (0.42) MEN1KMT2AHTTRIPK1ESR1
SCHEMBL13984232 0.73 RIPK1 (0.33) RIPK1ESR1SLC6A4
SCHEMBL24144240 0.70 GPR84 (0.67) SLC6A4
SCHEMBL6685097 0.69 RIPK1 (0.56) HTTRIPK1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C MEN1 1124/4885KMT2A 1971/4885HTT 3124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.