Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755639 | 0.89 | AVPR1A (0.38) | DRD2DRD3KCNH2AVPR1A | |
| SCHEMBL4755635 | 0.89 | AVPR1A (0.38) | DRD2DRD3KCNH2AVPR1A | |
| SCHEMBL13985227 | 0.86 | NOTUM (0.39) | DRD2DRD3KCNH2 | |
| SCHEMBL13985415 | 0.82 | AVPR1A (0.36) | DRD2DRD3KCNH2AVPR1ATRPV3 | |
| SCHEMBL4755622 | 0.81 | AVPR1A (0.37) | DRD2DRD3KCNH2AVPR1A | |
| SCHEMBL4755627 | 0.81 | AVPR1A (0.37) | DRD2DRD3KCNH2AVPR1A | |
| SCHEMBL13985299 | 0.81 | MCHR1 (0.35) | — | |
| SCHEMBL13985222 | 0.77 | AVPR1A (0.39) | TBK1DRD2DRD3KCNH2AVPR1A | |
| SCHEMBL13985528 | 0.77 | MCHR1 (0.38) | KCNH2AVPR1A | |
| Hydrochloric Acid SCHEMBL4755710 | 0.76 | AVPR1A (0.38) | TBK1DRD2DRD3KCNH2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |