Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755656 | 0.84 | MEN1 (0.39) | MCHR1GRIA2GRIN2AGRIN1ALDH1A1 | |
| SCHEMBL4755659 | 0.84 | MEN1 (0.39) | MCHR1GRIA2GRIN2AGRIN1ALDH1A1 | |
| SCHEMBL4755635 | 0.81 | AVPR1A (0.38) | MCHR1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL4755639 | 0.81 | AVPR1A (0.38) | MCHR1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL13985226 | 0.81 | TBK1 (0.33) | — | |
| SCHEMBL4755622 | 0.80 | AVPR1A (0.37) | MCHR1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL4755627 | 0.80 | AVPR1A (0.37) | MCHR1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL13985227 | 0.78 | NOTUM (0.39) | SCN9A | |
| SCHEMBL13985415 | 0.78 | AVPR1A (0.36) | MCHR1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13985528 | 0.78 | MCHR1 (0.38) | MCHR1ALDH1A1MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |