Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | BRD2 | P25440 | 2/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | USP14 | P54578 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755137 | 0.83 | AVPR1A (0.37) | CNR2CNR1MEN1KMT2AMAPT | |
| SCHEMBL4755132 | 0.83 | AVPR1A (0.37) | CNR2CNR1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL4822247 | 0.83 | AVPR1A (0.37) | CNR2CNR1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL4822238 | 0.83 | AVPR1A (0.37) | CNR2CNR1MEN1KMT2AMAPT | |
| SCHEMBL13985487 | 0.82 | OPRM1 (0.36) | BRD4BRD2BRD3CREBBPDGAT1 | |
| SCHEMBL4755166 | 0.78 | AVPR1A (0.39) | KMT2AKDM4EHPGDHSD17B10LMNA | |
| SCHEMBL4755169 | 0.78 | AVPR1A (0.39) | KMT2AKDM4EHPGDHSD17B10LMNA | |
| SCHEMBL4755075 | 0.78 | AVPR1A (0.37) | MEN1KMT2AMAPTKDM4EHPGD | |
| SCHEMBL4755083 | 0.78 | AVPR1A (0.37) | MEN1KMT2AMAPTKDM4EHPGD | |
| SCHEMBL4755639 | 0.76 | AVPR1A (0.38) | MEN1KMT2AMAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |