Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | DRD5 | P21918 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | USP14 | P54578 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985298 | 0.82 | BRD4 (0.37) | CNR1CNR2DGAT1USP14BRD4 | |
| SCHEMBL13985494 | 0.82 | MT-CO2 (0.34) | CNR1CNR2DRD1DRD5MEN1 | |
| SCHEMBL4753709 | 0.79 | DRD1 (0.40) | DRD1DRD5BRD4BRD2BRD3 | |
| SCHEMBL4753713 | 0.79 | DRD1 (0.40) | DRD1DRD5BRD4BRD2BRD3 | |
| SCHEMBL4755225 | 0.77 | DRD1 (0.40) | CNR1CNR2DRD1DRD5MAPT | |
| SCHEMBL4756551 | 0.77 | DRD1 (0.40) | CNR1CNR2DRD1DRD5MAPT | |
| SCHEMBL4755228 | 0.77 | DRD1 (0.40) | CNR1CNR2DRD1DRD5MAPT | |
| SCHEMBL13985493 | 0.75 | CNR1 (0.35) | CNR1CNR2DRD1DRD5USP14 | |
| SCHEMBL4755529 | 0.75 | DRD1 (0.39) | CNR1DRD1DRD5BRD4BRD2 | |
| SCHEMBL4755531 | 0.75 | DRD1 (0.39) | CNR1DRD1DRD5BRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |