Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 3/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 2/20 | 0.30 |
| ▸ | DRD5 | P21918 | 2/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755592 | 0.91 | DRD1 (0.37) | DRD1DRD5 | |
| SCHEMBL4755594 | 0.91 | DRD1 (0.37) | DRD1DRD5 | |
| SCHEMBL4755659 | 0.89 | MEN1 (0.39) | HCAR1 | |
| SCHEMBL4755656 | 0.89 | MEN1 (0.39) | HCAR1 | |
| SCHEMBL4755166 | 0.88 | AVPR1A (0.39) | AVPR1ADRD1DRD5CRHR1 | |
| SCHEMBL4755169 | 0.88 | AVPR1A (0.39) | AVPR1ADRD1DRD5CRHR1 | |
| SCHEMBL4755547 | 0.88 | MAPT (0.34) | TSHRSPRAVPR1AHCAR1 | |
| SCHEMBL4755551 | 0.88 | MAPT (0.34) | TSHRSPRAVPR1AHCAR1 | |
| SCHEMBL4755213 | 0.88 | DRD1 (0.40) | TSHRHCAR1DRD1DRD5NR1H2 | |
| SCHEMBL4755215 | 0.88 | DRD1 (0.40) | TSHRHCAR1DRD1DRD5NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |