Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755659 | 1.00 | MEN1 (0.39) | MEN1KMT2AMCHR1ALDH1A1NPC1 | |
| SCHEMBL4755594 | 0.92 | DRD1 (0.37) | MEN1KMT2AALDH1A1NPC1HPGD | |
| SCHEMBL4755592 | 0.92 | DRD1 (0.37) | MEN1KMT2AALDH1A1NPC1HPGD | |
| SCHEMBL4755547 | 0.89 | MAPT (0.34) | MEN1KMT2AMCHR1ALDH1A1HPGD | |
| SCHEMBL4755166 | 0.89 | AVPR1A (0.39) | KMT2AMCHR1ALDH1A1NPC1HPGD | |
| SCHEMBL13985302 | 0.89 | TSHR (0.31) | HCAR1 | |
| SCHEMBL4755551 | 0.89 | MAPT (0.34) | MEN1KMT2AMCHR1ALDH1A1HPGD | |
| SCHEMBL4755169 | 0.89 | AVPR1A (0.39) | KMT2AMCHR1ALDH1A1NPC1HPGD | |
| SCHEMBL4755213 | 0.89 | DRD1 (0.40) | MEN1KMT2AALDH1A1POLBHSD17B10 | |
| SCHEMBL4755215 | 0.89 | DRD1 (0.40) | MEN1KMT2AALDH1A1POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | claimed |